Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 4/20 | 0.47 |
| ▸ | CA1 | P00915 | 3/20 | 0.45 |
| ▸ | CA2 | P00918 | 3/20 | 0.45 |
| ▸ | CA4 | P22748 | 3/20 | 0.45 |
| ▸ | CA9 | Q16790 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 6/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 9/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
| ▸ | MMP8 | P22894 | 2/20 | 0.38 |
| ▸ | MMP3 | P08254 | 1/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.38 |
| ▸ | CTSB | P07858 | 2/20 | 0.37 |
| ▸ | F2 | P00734 | 1/20 | 0.37 |
| ▸ | CRHBP | P24387 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27434736 | 0.91 | PTGS2 (0.58) | PTGS2CA1CA2CA4CA9 | |
| SCHEMBL27433131 | 0.89 | PTGS2 (0.47) | PTGS2CA1CA2CA4CA9 | |
| SCHEMBL27484575 | 0.82 | MAPT (0.43) | PTGS2MAPTLMNAHTTSMN1; SMN2 | |
| SCHEMBL27484218 | 0.80 | MAPT (0.40) | PTGS2MAPTLMNAHTTSMN1; SMN2 | |
| SCHEMBL27460635 | 0.77 | MAPT (0.40) | PTGS2CA1CA2CA4MAPT | |
| SCHEMBL6341313 | 0.74 | PTGS2 (0.83) | PTGS2CA1CA2CA4CA9 | |
| SCHEMBL27433134 | 0.72 | MEN1 (0.44) | PTGS2MAPTLMNAHTTSMN1; SMN2 | |
| SCHEMBL27554099 | 0.72 | MEN1 (0.44) | PTGS2MAPTLMNAHTTSMN1; SMN2 | |
| SCHEMBL27484207 | 0.72 | MEN1 (0.51) | PTGS2MAPTHTTSMN1; SMN2KMT2A | |
| SCHEMBL27547013 | 0.71 | PTGS2 (0.44) | PTGS2MAPTLMNAKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1141630-A | Substituted pyrazolyl benzenesulfonamides for treating inflammation | SEARLE & CO (US) | 1997-01-29 | — | — | CN | claimed |
| CN-101242875-A | Ophthalmic composition containing mucoadhesive polysaccharides capable of promoting corneal re-epithelialization | OPOCRIN SPA (IT) | 2008-08-13 | — | — | CN | disclosed |
| CN-1137134-C | Polyfluoroalkyl tryptophan tripeptide thrombin inhibitors | ���µ�˹ҩ�﹫˾ | 2004-02-04 | — | — | CN | disclosed |
| CN-1127484-C | Substituted pyrazolyl benzene sulfone amides compounds for curing inflammation | SEARLE & CO (US) | 2003-11-12 | — | — | CN | disclosed |
| CN-1339020-A | Process for producing vitamin | DCV INC (US) | 2002-03-06 | — | — | CN | disclosed |
| CN-1280126-A | Substituted pyrazolyl benzenesulfonamides for treating inflammation | SEARLE & CO (US) | 2001-01-17 | — | — | CN | disclosed |
| CN-1280125-A | Substituted pyrazolyl benzene sulfone amides compounds for curing inflammation | SEARLE & CO (US) | 2001-01-17 | — | — | CN | disclosed |
| CN-1141630-A | Substituted pyrazolyl benzenesulfonamides for treating inflammation | SEARLE & CO (US) | 1997-01-29 | — | — | CN | disclosed |