Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NLRP3 | Q96P20 | 5/20 | 0.62 |
| ▸ | FBP1 | P09467 | 2/20 | 0.47 |
| ▸ | GSTO1 | P78417 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27437801 | 0.96 | NLRP3 (0.64) | NLRP3FBP1GSTO1MEN1HTT | |
| SCHEMBL27433352 | 0.85 | NLRP3 (0.70) | NLRP3FBP1 | |
| SCHEMBL7144737 | 0.82 | NLRP3 (0.66) | NLRP3FBP1GSTO1KMT2A | |
| SCHEMBL7137648 | 0.80 | NLRP3 (0.69) | NLRP3FBP1GSTO1KMT2A | |
| SCHEMBL7613905 | 0.79 | NLRP3 (0.61) | NLRP3FBP1GSTO1KMT2A | |
| SCHEMBL7137330 | 0.78 | NLRP3 (0.76) | NLRP3FBP1 | |
| SCHEMBL6555763 | 0.78 | NLRP3 (0.76) | NLRP3FBP1 | |
| SCHEMBL7142667 | 0.78 | NLRP3 (0.74) | NLRP3FBP1 | |
| SCHEMBL7141185 | 0.77 | NLRP3 (0.72) | NLRP3FBP1 | |
| SCHEMBL6513806 | 0.77 | NLRP3 (1.00) | NLRP3FBP1GSTO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1127479-C | Sulfonylurea derivatives and their use in the control of interleukin-1 activity | PFIZER (US) | 2003-11-12 | — | — | CN | disclosed |
| CN-1245490-A | Sulfonyl urea derivatives and their use in control of interleukin-1 activity | PFIZER (US) | 2000-02-23 | — | — | CN | disclosed |