Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS2 | P35228 | 20/20 | 0.76 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5191473 | 0.91 | NOS2 (0.77) | NOS2 | |
| SCHEMBL7237761 | 0.90 | NOS2 (0.73) | NOS2 | |
| SCHEMBL5189695 | 0.90 | NOS2 (0.78) | NOS2 | |
| SCHEMBL5194906 | 0.90 | NOS2 (0.78) | NOS2 | |
| SCHEMBL5193298 | 0.89 | NOS2 (0.64) | NOS2 | |
| SCHEMBL5192524 | 0.88 | NOS2 (0.77) | NOS2 | |
| SCHEMBL5194766 | 0.88 | NOS2 (0.80) | NOS2 | |
| SCHEMBL5190273 | 0.88 | NOS2 (0.67) | NOS2 | |
| SCHEMBL5192782 | 0.88 | NOS2 (0.67) | NOS2 | |
| SCHEMBL5189764 | 0.88 | NOS2 (0.67) | NOS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1100777-C | N-heterocyclic derivatives as NOS inhibitor | BERLEX LAB (US) | 2003-02-05 | — | — | CN | claimed |
| CN-1252799-A | N-heterocyclic derivatives as NOS inhibitor | BERLEX LAB (US) | 2000-05-10 | — | — | CN | claimed |
| CN-1100777-C | N-heterocyclic derivatives as NOS inhibitor | BERLEX LAB (US) | 2003-02-05 | — | — | CN | disclosed |
| CN-1252799-A | N-heterocyclic derivatives as NOS inhibitor | BERLEX LAB (US) | 2000-05-10 | — | — | CN | disclosed |