SCHEMBL27435335

SCHEMBL27435335

CCN1CCOc2c1cc(Cl)c(OC)c2C(=O)O

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 3/20 0.40
HSD17B10 Q99714 2/20 0.40
ALDH1A1 P00352 1/20 0.40
DRD2 P14416 6/20 0.39
DRD3 P35462 6/20 0.39
DRD4 P21917 4/20 0.39
CYP1A2 P05177 3/20 0.39
CYP2D6 P10635 3/20 0.39
DRD1 P21728 2/20 0.39
DRD5 P21918 2/20 0.39
KMT2A Q03164 2/20 0.39
CYP2C9 P11712 1/20 0.39
CYP2C19 P33261 1/20 0.39
HTR1A P08908 1/20 0.36
HTR2A P28223 1/20 0.36
HTR2C P28335 1/20 0.36
MEN1 O00255 1/20 0.35
LMNA P02545 1/20 0.35
HIF1A Q16665 1/20 0.35
TPMT P51580 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30954160 1.00 KDM4E (0.40) KDM4EHSD17B10ALDH1A1DRD2DRD3
SCHEMBL27435327 0.89 DRD2 (0.40) KDM4EHSD17B10DRD2DRD3DRD4
SCHEMBL27435528 0.86 KCNA3 (0.41) KDM4EHSD17B10ALDH1A1DRD2DRD3
SCHEMBL30954067 0.85 TP53 (0.42) KDM4EHSD17B10ALDH1A1KMT2AMEN1
SCHEMBL27435254 0.85 TP53 (0.42) KDM4EHSD17B10ALDH1A1KMT2AMEN1
SCHEMBL27432464 0.84 KDM4E (0.43) KDM4EHSD17B10ALDH1A1DRD2DRD3
SCHEMBL30954108 0.84 KDM4E (0.43) KDM4EHSD17B10ALDH1A1DRD2DRD3
SCHEMBL30954157 0.84 CHRM1 (0.37) KDM4ECYP1A2CYP2C19LMNATP53
SCHEMBL27434015 0.84 CHRM1 (0.37) KDM4ECYP1A2CYP2C19LMNATP53
SCHEMBL30954054 0.84 KCNA3 (0.43) KDM4EHSD17B10ALDH1A1DRD2DRD3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4630412-A1 COMPOUNDS FOR THE TREATMENT OF NEUROMUSCULAR DISORDERS NMD Pharma A/S (DK) 2025-10-15 EP claimed
WO-2024121130-A1 COMPOUNDS FOR THE TREATMENT OF NEUROMUSCULAR DISORDERS NMD PHARMA A/S (DK) 2024-06-13 WO claimed
EP-4630412-A1 COMPOUNDS FOR THE TREATMENT OF NEUROMUSCULAR DISORDERS NMD Pharma A/S (DK) 2025-10-15 EP disclosed
WO-2024121130-A1 COMPOUNDS FOR THE TREATMENT OF NEUROMUSCULAR DISORDERS NMD PHARMA A/S (DK) 2024-06-13 WO disclosed
WO-2024121130-A1 COMPOUNDS FOR THE TREATMENT OF NEUROMUSCULAR DISORDERS NMD PHARMA A/S (DK) 2024-06-13 WO disclosed