Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4F2 | P78329 | 1/20 | 0.36 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.31 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.31 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.31 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5634801 | 0.90 | CYP2D6 (0.38) | CYP4F2CYP4A11CYP2D6SLC6A2SLC6A4 | |
| SCHEMBL18044818 | 0.87 | CYP4F2 (0.43) | CYP4F2CYP4A11DGAT1 | |
| Toluene SCHEMBL27486527 | 0.86 | OPRM1 (0.44) | OPRM1CYP2D6SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL25273742 | 0.84 | CYP4F2 (0.37) | CYP4F2CYP4A11KDM4EKMT2AOPRM1 | |
| SCHEMBL782051 | 0.84 | CYP4F2 (0.38) | CYP4F2CYP4A11DGAT1 | |
| SCHEMBL15268879 | 0.84 | CYP4F2 (0.38) | CYP4F2CYP4A11DGAT1 | |
| SCHEMBL28170312 | 0.83 | CYP4F2 (0.36) | CYP4F2CYP4A11KDM4EKMT2AOPRM1 | |
| SCHEMBL27427642 | 0.82 | CYP4F2 (0.35) | CYP4F2CYP4A11 | |
| SCHEMBL3295173 | 0.82 | CYP4F2 (0.38) | CYP4F2CYP4A11DGAT1 | |
| SCHEMBL7370030 | 0.80 | KDM4E (0.40) | CYP4F2CYP4A11KDM4EKMT2AOPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1106400-A | Heteroarylpiperidines, process for their preparation and pharmaceutical compositions in which they are present | SANOFI SA (FR) | 1995-08-09 | — | — | CN | disclosed |