Known targets — ChEMBL curated mechanism
MMP1MMP13MMP7MMP8polrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Alcohol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Alcohol SCHEMBL28233814 | 0.82 | — | — | |
| Alcohol SCHEMBL8234061 | 0.82 | — | — | |
| Alcohol SCHEMBL29975647 | 0.82 | — | — | |
| Alcohol SCHEMBL6910520 | 0.82 | TSHR (1.00) | — | |
| Alcohol SCHEMBL9461084 | 0.82 | TSHR (1.00) | — | |
| Alcohol SCHEMBL463 | 0.82 | — | — | |
| Alcohol SCHEMBL2464657 | 0.82 | TSHR (1.00) | — | |
| Alcohol SCHEMBL54946 | 0.82 | — | — | |
| Alcohol SCHEMBL17770701 | 0.82 | — | — | |
| Alcohol SCHEMBL27342073 | 0.82 | TSHR (1.00) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101384591-A | Antiviral compounds | ABBOTT LAB (US) | 2009-03-11 | — | — | CN | disclosed |
| CN-101365684-A | Indazole derivatives inhibiting TRPV1 receptor | ABBOTT LAB (US) | 2009-02-11 | — | — | CN | disclosed |
| CN-100390169-C | Hydroxymethyl substituted dihydroisoxazole derivatives useful as antibiotic agents | ASTRAZENECA AB (SE) | 2008-05-28 | — | — | CN | disclosed |
| CN-100354265-C | Pharmaceutical compounds | XENOVA LTD (GB) | 2007-12-12 | — | — | CN | disclosed |
| CN-1733779-A | Novel phosphorus-containing prodrug | METABASIS THERAPEUTICS INC (US) | 2006-02-15 | — | — | CN | disclosed |
| CN-1723204-A | Benzoxazole derivatives and their use as adenosine receptor ligands | HOFFMANN LA ROCHE (CH) | 2006-01-18 | — | — | CN | disclosed |
| CN-1527830-A | Ether derivatives useful as inhibitors of PDE4 isozymes | �Ʒ� | 2004-09-08 | — | — | CN | disclosed |
| CN-1450990-A | Inhibitors of neuraminidase | ABBOTT LAB (US) | 2003-10-22 | — | — | CN | disclosed |
| CN-1100774-C | Compounds having both potent calcium antagonist and antioxidant activity and use thereof as cytoprotective agents | ALCON LAB INC (US) | 2003-02-05 | — | — | CN | disclosed |
| CN-1305477-A | Azablicyclic 5-HT, receptor ligands | PFIZER PROD INC (US) | 2001-07-25 | — | — | CN | disclosed |
| CN-1296481-A | (4-arylsulfonylamino) -tetrahydropyran-4-carboxylic acid hydroxyamides | PFIZER PROD INC (US) | 2001-05-23 | — | — | CN | disclosed |
| CN-1284944-A | Integrin receptor antagonists | MERCK & CO INC (US) | 2001-02-21 | — | — | CN | disclosed |
| CN-1117292-A | Compounds having both potent calcium antagonist and antioxidant activity and use thereof as cytoprotective agents | ALCON LAB INC (US) | 1996-02-21 | — | — | CN | disclosed |