SCHEMBL27436747

SCHEMBL27436747

Oc1ccc(OCc2cccc(OCc3ccccc3)c2)cc1Cl

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP4F2 P78329 1/20 0.56
CYP4A11 Q02928 1/20 0.56
MAOB P27338 8/20 0.55
MRGPRX4 Q96LA9 1/20 0.55
FFAR1 O14842 1/20 0.55
LMNA P02545 1/20 0.53
CYP1A2 P05177 1/20 0.53
PTGS1 P23219 1/20 0.53
SLC6A2 P23975 1/20 0.53
CYP2C19 P33261 1/20 0.53
PTGS2 P35354 1/20 0.53
SLC6A3 Q01959 1/20 0.53
HIF1A Q16665 1/20 0.53
HDAC6 Q9UBN7 1/20 0.53
BCHE P06276 2/20 0.53
MEN1 O00255 2/20 0.52
RAB9A P51151 2/20 0.52
KMT2A Q03164 2/20 0.52
KDM4E B2RXH2 1/20 0.52
ALDH1A1 P00352 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1532839 0.94 LMNA (0.59) CYP4F2CYP4A11MAOBMRGPRX4LMNA
SCHEMBL27457931 0.86 FFAR1 (0.50) MAOBMRGPRX4FFAR1LMNAALDH1A1
SCHEMBL27433328 0.85 ESR2 (0.57) MAOBFFAR1LMNACYP1A2PTGS1
SCHEMBL27486567 0.85 MRGPRX4 (0.51) MAOBMRGPRX4MAPTTHRBL3MBTL1
SCHEMBL27501493 0.84 MAPT (0.62) MAOBMRGPRX4FFAR1MAPTL3MBTL1
SCHEMBL27486568 0.84 FFAR1 (0.48) MAOBMRGPRX4FFAR1LMNAMEN1
SCHEMBL27460760 0.84 FFAR1 (0.57) MAOBMRGPRX4FFAR1MAOA
SCHEMBL27435939 0.84 MAOB (0.60) MAOBMRGPRX4FFAR1MAOA
SCHEMBL27540584 0.84 MAOB (0.69) MAOBMRGPRX4FFAR1MAOA
SCHEMBL4346964 0.83 MAPT (0.72) MAOBFFAR1LMNABCHEMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1128777-C Dihalopropene compounds, insecticidal/acaricidal agents containing same, and intermediates for their production SUMITOMO CHEMICAL CO (JP) 2003-11-26 CN disclosed
CN-1137265-A Dihalopropene compounds, insecticides/acaricides containing the same and intermediates for their production SUMITOMO CHEMICAL CO (JP) 1996-12-04 CN disclosed