SCHEMBL27436751

SCHEMBL27436751

Oc1ccc(OCCCC(F)(F)F)cc1Cl

nearest known ligand 0.51

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
MAOB P27338 3/20 0.51
MAOA P21397 1/20 0.40
PDE2A O00408 3/20 0.40
APP P05067 1/20 0.40
KDM4E B2RXH2 1/20 0.39
ADRB2 P07550 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
CACNA1B Q00975 1/20 0.38
KCNH2 Q12809 1/20 0.38
CYP2C9 P11712 1/20 0.37
MOGAT2 Q3SYC2 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27436750 0.95 MAOB (0.47) MAOBMAOAPDE2AKDM4EADRB2
SCHEMBL4450625 0.81 CYP2C9 (0.45) KDM4ESMN1; SMN2CYP2C9
SCHEMBL17912821 0.80 LTA4H (0.50) KDM4EADRB2SMN1; SMN2KCNH2
SCHEMBL27459585 0.79 POLB (0.49)
SCHEMBL27625868 0.78 SMN1; SMN2 (0.47) PDE2AKDM4EADRB2SMN1; SMN2
SCHEMBL27433270 0.78 TSHR (0.50) MAOBKCNH2
SCHEMBL27433268 0.78 TSHR (0.50) MAOBMAOAKDM4EKCNH2
SCHEMBL8659600 0.78 PPARA (0.39) KDM4EADRB2SMN1; SMN2CYP2C9
SCHEMBL18725098 0.77 MAOB (0.51) MAOBMAOAPDE2AAPPCACNA1B
SCHEMBL2567562 0.77 LTA4H (0.55) MAOBAPP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1128777-C Dihalopropene compounds, insecticidal/acaricidal agents containing same, and intermediates for their production SUMITOMO CHEMICAL CO (JP) 2003-11-26 CN disclosed
CN-1137265-A Dihalopropene compounds, insecticides/acaricides containing the same and intermediates for their production SUMITOMO CHEMICAL CO (JP) 1996-12-04 CN disclosed