Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | MME | P08473 | 2/20 | 0.37 |
| ▸ | ACE | P12821 | 2/20 | 0.37 |
| ▸ | CPA1 | P15085 | 2/20 | 0.37 |
| ▸ | ACE2 | Q9BYF1 | 2/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.36 |
| ▸ | HRH1 | P35367 | 1/20 | 0.36 |
| ▸ | DRD3 | P35462 | 1/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | ENPEP | Q07075 | 2/20 | 0.36 |
| ▸ | CA2 | P00918 | 3/20 | 0.34 |
| ▸ | CA1 | P00915 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19712061 | 0.80 | TDP1 (0.37) | MMEADRA1ATDP1TP53 | |
| SCHEMBL11590567 | 0.77 | TDP1 (0.41) | CHRM1AKR1A1CHRM3HTR2AHTR2C | |
| SCHEMBL538319 | 0.75 | TP53 (0.38) | CHRM1AKR1A1CHRM3HTR2AHTR2C | |
| SCHEMBL7498163 | 0.75 | ALDH1A1 (0.34) | ALDH1A1MMEACECPA1ACE2 | |
| SCHEMBL7501293 | 0.75 | ALDH1A1 (0.34) | ALDH1A1MMEACECPA1ACE2 | |
| SCHEMBL7496898 | 0.75 | ALDH1A1 (0.34) | ALDH1A1MMEACECPA1ACE2 | |
| SCHEMBL7496903 | 0.75 | ALDH1A1 (0.34) | ALDH1A1MMEACECPA1ACE2 | |
| SCHEMBL7499567 | 0.75 | ALDH1A1 (0.34) | ALDH1A1MMEACECPA1ACE2 | |
| SCHEMBL1129743 | 0.74 | SRC (0.39) | ALDH1A1TDP1TP53 | |
| SCHEMBL2723014 | 0.73 | TP53 (0.36) | TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1134152-A | Substituted thiazolo [3, 2-alpha ] aza * derivatives | EISAI CO LTD (JP) | 1996-10-23 | — | — | CN | claimed |
| CN-1170832-C | Substituted thiazol [3,2-alpha] azatropylidene derivatives | ������������ʽ���� | 2004-10-13 | — | — | CN | disclosed |
| CN-1262275-A | Substituted thiazol [3,2-alpha] azatropylidene derivatives | EISAI CO LTD (JP) | 2000-08-09 | — | — | CN | disclosed |
| CN-1053908-C | Substituted thiazolo [3, 2-alpha ] aza * derivatives | EISAI CO LTD (JP) | 2000-06-28 | — | — | CN | disclosed |
| CN-1134152-A | Substituted thiazolo [3, 2-alpha ] aza * derivatives | EISAI CO LTD (JP) | 1996-10-23 | — | — | CN | disclosed |