Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH2 | P05091 | 9/20 | 0.56 |
| ▸ | MAOA | P21397 | 8/20 | 0.56 |
| ▸ | MAOB | P27338 | 8/20 | 0.56 |
| ▸ | ACSL1 | P33121 | 2/20 | 0.49 |
| ▸ | ACSL6 | Q9UKU0 | 2/20 | 0.49 |
| ▸ | MAP1LC3B | Q9GZQ8 | 1/20 | 0.48 |
| ▸ | MAP1LC3A | Q9H492 | 1/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.48 |
| ▸ | PLA2G4B | P0C869 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | GPR17 | Q13304 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6275338 | 1.00 | ALDH2 (0.56) | ALDH2MAOAMAOBACSL1ACSL6 | |
| SCHEMBL27440430 | 1.00 | ALDH2 (0.56) | ALDH2MAOAMAOBACSL1ACSL6 | |
| SCHEMBL6277088 | 1.00 | ALDH2 (0.56) | ALDH2MAOAMAOBACSL1ACSL6 | |
| SCHEMBL27443884 | 0.99 | ALDH2 (0.57) | ALDH2MAOAMAOBACSL1ACSL6 | |
| SCHEMBL6270807 | 0.98 | ALDH2 (0.53) | ALDH2MAOAMAOBACSL1ACSL6 | |
| SCHEMBL6276873 | 0.98 | ALDH2 (0.53) | ALDH2MAOAMAOBACSL1ACSL6 | |
| SCHEMBL6276076 | 0.98 | ALDH2 (0.55) | ALDH2MAOAMAOBACSL1ACSL6 | |
| SCHEMBL6276248 | 0.96 | ALDH2 (0.51) | ALDH2MAOAMAOBACSL1ACSL6 | |
| SCHEMBL6270780 | 0.96 | ALDH2 (0.51) | ALDH2MAOAMAOBACSL1ACSL6 | |
| SCHEMBL6276032 | 0.95 | MAOA (0.51) | ALDH2MAOAMAOBACSL1ACSL6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1101678-C | Benzopyran derivative and therapeutic agent for heart disease containing the same as active ingredient | DAINIPPON INK & CHEMICALS (JP) | 2003-02-19 | — | — | CN | disclosed |
| CN-1164999-A | Benzopyran derivative and therapeutic agent for heart disease containing the same as active ingredient | DAINIPPON INK & CHEMICALS (JP) | 1997-11-19 | — | — | CN | disclosed |