Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 2/20 | 0.47 |
| ▸ | MCHR1 | Q99705 | 5/20 | 0.47 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.46 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.42 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12449705 | 0.89 | NOTUM (0.55) | USP2PDK2HTTNPSR1NOTUM | |
| SCHEMBL12839 | 0.89 | NOTUM (0.55) | USP2PDK2HTTNPSR1NOTUM | |
| SCHEMBL12449707 | 0.89 | NOTUM (0.55) | USP2PDK2HTTNPSR1NOTUM | |
| SCHEMBL24418020 | 0.84 | ALDH1A1 (0.46) | USP2MCHR1PDK2HRH3HTT | |
| Nitrogen SCHEMBL11225878 | 0.81 | NOTUM (0.45) | USP2PDK2HTTNPSR1NOTUM | |
| SCHEMBL19314278 | 0.79 | USP2 (0.47) | USP2PDK2HTTNPSR1MEN1 | |
| SCHEMBL21460344 | 0.79 | NAMPT (0.50) | MCHR1HRH3NOTUM | |
| SCHEMBL21460347 | 0.79 | NAMPT (0.50) | MCHR1HRH3NOTUM | |
| SCHEMBL13056 | 0.78 | MAPT (0.52) | HTTNOTUMMEN1KMT2ANPC1 | |
| SCHEMBL12919 | 0.78 | MAPT (0.52) | HTTNOTUMMEN1KMT2ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4393923-A1 | PYRIDO RING COMPOUND, PREPARATION METHOD THEREFOR, INTERMEDIATE, COMPOSITION, AND APPLICATION | Yiyou Biotech (Shanghai) Co., Ltd. (CN) | 2024-07-03 | — | — | EP | disclosed |