Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 2/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.42 |
| ▸ | TACR1 | P25103 | 3/20 | 0.41 |
| ▸ | SLC1A3 | P43003 | 2/20 | 0.41 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.41 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.39 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.39 |
| ▸ | IDO1 | P14902 | 1/20 | 0.37 |
| ▸ | AGXT | P21549 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9117050 | 0.82 | TACR1 (0.52) | SLC6A2SLC6A4SLC6A3TACR1SLC1A3 | |
| SCHEMBL27443072 | 0.81 | SLC1A3 (0.44) | SLC6A2SLC6A4SLC6A3TACR1SLC1A3 | |
| SCHEMBL8333871 | 0.81 | SLC6A2 (0.42) | SLC6A2SLC6A4SLC6A3TACR1SLC1A3 | |
| SCHEMBL27481651 | 0.80 | SLC1A3 (0.42) | SLC6A2SLC6A4SLC6A3TACR1SLC1A3 | |
| SCHEMBL8338564 | 0.77 | TACR1 (0.45) | SLC6A2SLC6A4SLC6A3TACR1SLC1A1 | |
| SCHEMBL27928229 | 0.75 | SLC6A2 (0.31) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL27710223 | 0.72 | ALDH1A1 (0.41) | KMT2AMEN1TSHRSMN1; SMN2 | |
| SCHEMBL7013321 | 0.71 | GRIN2D (0.42) | SLC6A2SLC6A4SLC6A3CYP1A2CYP2D6 | |
| SCHEMBL6753036 | 0.71 | GRIN2D (0.42) | SLC6A2SLC6A4SLC6A3CYP1A2CYP2D6 | |
| SCHEMBL992838 | 0.71 | IDO1 (0.47) | SLC6A2SLC6A4SLC6A3TACR1SLC1A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1122033-C | Triazolopurine derivatives, pharmaceutical compositions containing the same | OTSUKE PHARMACEUTICAL FACTORY (JP) | 2003-09-24 | — | — | CN | disclosed |
| CN-1301266-A | Triazolopurine derivatives, pharmaceutical composition containing the same, adenosine A3 receptor affinity agent, and asthma therapeutic agent | OTSUKA PHARMACEUITCAL FACTORY (JP) | 2001-06-27 | — | — | CN | disclosed |