SCHEMBL27439693

SCHEMBL27439693

COc1ccc2c([nH]c3ccccc32)c1C

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 6/20 0.54
KDM4E B2RXH2 4/20 0.54
ALDH1A1 P00352 4/20 0.54
HSD17B10 Q99714 4/20 0.54
MEN1 O00255 4/20 0.54
KMT2A Q03164 4/20 0.54
MAPK1 P28482 3/20 0.54
HPGD P15428 3/20 0.54
CYP1A2 P05177 2/20 0.54
CYP3A4 P08684 2/20 0.54
THRB P10828 1/20 0.54
CYP2C9 P11712 1/20 0.54
ALOX15 P16050 1/20 0.54
ALOX12 P18054 1/20 0.54
CASP1 P29466 1/20 0.54
CASP7 P55210 1/20 0.54
TDP1 Q9NUW8 1/20 0.54
KIF11 P52732 4/20 0.53
ATM Q13315 1/20 0.53
NPSR1 Q6W5P4 2/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30338322 0.83 KDM4E (0.54) MAPTKDM4EALDH1A1HSD17B10MEN1
SCHEMBL17941705 0.83 KDM4E (0.54) MAPTKDM4EALDH1A1HSD17B10MEN1
SCHEMBL17950574 0.81 MAPT (0.53) MAPTKDM4EALDH1A1HSD17B10MEN1
SCHEMBL28644669 0.81 MAPT (0.53) MAPTKDM4EALDH1A1HSD17B10MEN1
SCHEMBL28651833 0.81 MAPT (0.53) MAPTKDM4EALDH1A1HSD17B10MEN1
SCHEMBL896249 0.80 KDM4E (0.58) MAPTKDM4EALDH1A1HSD17B10MEN1
SCHEMBL29446056 0.80 KDM4E (0.58) MAPTKDM4EALDH1A1HSD17B10MEN1
SCHEMBL28281488 0.80 MAPT (0.54) MAPTKDM4EALDH1A1HSD17B10MEN1
SCHEMBL9056003 0.80 SLC22A6 (0.51) MAPTKDM4EALDH1A1HSD17B10MEN1
SCHEMBL28285737 0.79 MAPT (0.50) MAPTKDM4EALDH1A1HSD17B10MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240224783-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2024-07-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240224783-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD2, OCIAD1, ICOSLG MAPT 1653/4885KDM4E 3179/4885ALDH1A1 149/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.