Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.51 |
| ▸ | GSK3B | P49841 | 2/20 | 0.48 |
| ▸ | ADK | P55263 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | KIF11 | P52732 | 3/20 | 0.46 |
| ▸ | PARP14 | Q460N5 | 2/20 | 0.44 |
| ▸ | PIM1 | P11309 | 1/20 | 0.43 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.43 |
| ▸ | MPL | P40238 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | GABRP | O00591 | 2/20 | 0.42 |
| ▸ | GABRD | O14764 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4786156 | 0.83 | SLC22A6 (0.55) | SLC22A6GSK3BADKMAPTHTT | |
| SCHEMBL8801909 | 0.82 | SLC22A6 (0.48) | SLC22A6GSK3BADKMAPTMAPK1 | |
| SCHEMBL27439693 | 0.80 | MAPT (0.54) | MAPTMAPK1NPSR1KIF11KDM4E | |
| SCHEMBL8387341 | 0.77 | KIF11 (0.50) | MAPTMAPK1NPSR1HTTKIF11 | |
| SCHEMBL31124833 | 0.77 | KIF11 (0.50) | MAPTMAPK1NPSR1HTTKIF11 | |
| Acetic Acid SCHEMBL11537832 | 0.76 | MPL (0.51) | MAPTMAPK1NPSR1KIF11PARP14 | |
| SCHEMBL8087797 | 0.74 | GSK3B (0.63) | SLC22A6GSK3BADKMAPTNPSR1 | |
| SCHEMBL8389062 | 0.74 | MPL (0.56) | MAPTMAPK1NPSR1KIF11PARP14 | |
| SCHEMBL4185213 | 0.73 | ACHE (0.57) | SLC22A6MAPTMAPK1HTTKDM4E | |
| SCHEMBL5964419 | 0.73 | KIF11 (0.56) | MAPTMAPK1NPSR1KIF11PARP14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1166169-A | Heterocyclic compounds, useful as allosteric effectors at muscarinic receptors | SANKYO CO (JP) | 1997-11-26 | — | — | CN | disclosed |
| WO-1996003377-A1 | HETEROCYCLIC COMPOUNDS, USEFUL AS ALLOSTERIC EFFECTORS AT MUSCARINIC RECEPTORS | SANKYO COMPANY, LIMITED (JP) | 1996-02-08 | — | — | WO | disclosed |