SCHEMBL274401

SCHEMBL274401

CCN(CC)CCN(C)Cc1cccc(C(=O)Nc2sc3c(c2C(=O)N/N=C/c2ccc(C)cc2)CCCC3)c1

nearest known ligand 0.59

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
SLC34A2 O95436 6/20 0.59
FLT3 P36888 2/20 0.48
MEN1 O00255 4/20 0.47
KMT2A Q03164 4/20 0.47
TP53 P04637 3/20 0.47
MAPT P10636 3/20 0.47
NPC1 O15118 2/20 0.46
RAB9A P51151 1/20 0.46
POLB P06746 1/20 0.46
NPSR1 Q6W5P4 1/20 0.46
KIF11 P52732 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL267607 1.00 SLC34A2 (0.59) SLC34A2FLT3MEN1KMT2ATP53
SCHEMBL266920 0.95 SLC34A2 (0.55) SLC34A2FLT3MEN1KMT2ATP53
SCHEMBL266919 0.95 SLC34A2 (0.55) SLC34A2FLT3MEN1KMT2ATP53
SCHEMBL265543 0.94 SLC34A2 (0.60) SLC34A2FLT3MEN1KMT2ATP53
SCHEMBL265544 0.94 SLC34A2 (0.60) SLC34A2FLT3MEN1KMT2ATP53
SCHEMBL267252 0.94 SLC34A2 (0.60) SLC34A2FLT3MEN1KMT2ATP53
SCHEMBL274205 0.94 SLC34A2 (0.60) SLC34A2FLT3MEN1KMT2ATP53
SCHEMBL273811 0.92 SLC34A2 (0.57) SLC34A2FLT3MEN1KMT2ATP53
SCHEMBL270095 0.92 SLC34A2 (0.57) SLC34A2FLT3MEN1KMT2ATP53
SCHEMBL265885 0.92 SLC34A2 (0.52) SLC34A2FLT3MEN1KMT2ATP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20120115851-A1 COMPOUND INHIBITING IN VIVO PHOSPHORUS TRANSPORT AND MEDICINE CONTAINING THE SAME KYOWA HAKKO KIRIN CO., LTD. (JP) 2012-05-10 US disclosed
US-20120115851-A1 COMPOUND INHIBITING IN VIVO PHOSPHORUS TRANSPORT AND MEDICINE CONTAINING THE SAME KYOWA HAKKO KIRIN CO., LTD. (JP) 2012-05-10 US disclosed
US-8134015-B2 Compound inhibiting in vivo phosphorous transport and medicine containing the same KYOWA HAKKO KIRIN CO., LTD. (JP) 2012-03-13 US disclosed
US-8134015-B2 Compound inhibiting in vivo phosphorous transport and medicine containing the same KYOWA HAKKO KIRIN CO., LTD. (JP) 2012-03-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120115851-A1 COMPOUND INHIBITING IN VIVO PHOSPHORUS TRANSPORT AND MEDICINE CONTAINING THE SAME SLC34A1, SLC34A2, SLC20A2 SLC34A2 2/4885FLT3 2535/4885MEN1 1638/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.