Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP2 | Q13822 | 1/20 | 0.52 |
| ▸ | APP | P05067 | 4/20 | 0.50 |
| ▸ | SNCA | P37840 | 4/20 | 0.50 |
| ▸ | ESRRA | P11474 | 1/20 | 0.43 |
| ▸ | SLC16A1 | P53985 | 3/20 | 0.41 |
| ▸ | SLC16A3 | O15427 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.39 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31050165 | 0.87 | APP (0.55) | ENPP2APPSNCALMNAKDM4E | |
| SCHEMBL27440440 | 0.87 | APP (0.55) | ENPP2APPSNCALMNAKDM4E | |
| SCHEMBL27440296 | 0.85 | ESRRA (0.49) | ENPP2APPSNCAESRRASLC16A1 | |
| SCHEMBL31050166 | 0.85 | ESRRA (0.49) | ENPP2APPSNCAESRRASLC16A1 | |
| SCHEMBL31050168 | 0.84 | APP (0.52) | ENPP2APPSNCALMNAKDM4E | |
| SCHEMBL27440481 | 0.84 | APP (0.52) | ENPP2APPSNCALMNAKDM4E | |
| SCHEMBL31050170 | 0.84 | APP (0.50) | ENPP2APPSNCAESRRASLC16A1 | |
| SCHEMBL27440290 | 0.84 | APP (0.50) | ENPP2APPSNCAESRRASLC16A1 | |
| SCHEMBL26116453 | 0.83 | SNCA (0.60) | ENPP2APPSNCALMNAKDM4E | |
| SCHEMBL25424902 | 0.83 | APP (0.57) | ENPP2APPSNCALMNAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4642783-A1 | COMPOUNDS FOR TREATMENT OF HAIR LOSS | Pelage Pharmaceuticals, Inc. (US) | 2025-11-05 | — | — | EP | disclosed |
| WO-2024145369-A1 | COMPOUNDS FOR TREATMENT OF HAIR LOSS | PELAGE PHARMACEUTICALS, INC. (US) | 2024-07-04 | — | — | WO | disclosed |
| WO-2024145369-A1 | COMPOUNDS FOR TREATMENT OF HAIR LOSS | PELAGE PHARMACEUTICALS, INC. (US) | 2024-07-04 | — | — | WO | disclosed |