Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 4/20 | 0.50 |
| ▸ | SNCA | P37840 | 4/20 | 0.50 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | SLC16A1 | P53985 | 4/20 | 0.40 |
| ▸ | SLC16A3 | O15427 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | THRB | P10828 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | ESRRA | P11474 | 1/20 | 0.38 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.38 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31050170 | 1.00 | APP (0.50) | APPSNCAENPP2MAPTSMN1; SMN2 | |
| SCHEMBL27440596 | 0.93 | ENPP2 (0.48) | APPSNCAENPP2MAPTSMN1; SMN2 | |
| SCHEMBL28377102 | 0.92 | APP (0.57) | APPSNCAENPP2MAPTALDH1A1 | |
| SCHEMBL20603144 | 0.92 | APP (0.57) | APPSNCAENPP2MAPTALDH1A1 | |
| SCHEMBL27440285 | 0.89 | APP (0.52) | APPSNCAENPP2MAPTALDH1A1 | |
| SCHEMBL26552405 | 0.89 | APP (0.52) | APPSNCAENPP2MAPTSMN1; SMN2 | |
| SCHEMBL31050160 | 0.87 | APP (0.55) | APPSNCAENPP2MAPTSMN1; SMN2 | |
| SCHEMBL27440401 | 0.87 | APP (0.55) | APPSNCAENPP2MAPTSMN1; SMN2 | |
| SCHEMBL30426119 | 0.86 | APP (0.55) | APPSNCAENPP2ALDH1A1LMNA | |
| SCHEMBL25424902 | 0.86 | APP (0.57) | APPSNCAENPP2ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024145369-A1 | COMPOUNDS FOR TREATMENT OF HAIR LOSS | PELAGE PHARMACEUTICALS, INC. (US) | 2024-07-04 | — | — | WO | disclosed |