SCHEMBL2744144

SCHEMBL2744144

C#CCOCO

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ethylene Glycol SCHEMBL9492826 0.80 ALDH1A1 (0.41)
SCHEMBL27741470 0.80 ALDH1A1 (0.60)
SCHEMBL27741471 0.78 TSHR (0.42)
SCHEMBL39635 0.78
1,4-Butanediol SCHEMBL17186654 0.75 TSHR (0.43)
SCHEMBL1029887 0.75
Lithium SCHEMBL11693507 0.74
SCHEMBL11569436 0.74
SCHEMBL6790137 0.74
SCHEMBL4352824 0.73 TSHR (0.37)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3095778-B1 OXIME ESTER FLUORENE COMPOUND, PHOTOPOLYMERIZATION INITIATOR COMPRISING IT, PHOTORESIST COMPOSITION, USES OF THE PHOTORESIST COMPOSITION SAMYANG CORP (KR) 2020-12-16 EP claimed
EP-3193880-B1 INHIBITING THE TRANSIENT RECEPTOR POTENTIAL A1 ION CHANNEL LILLY CO ELI (US) 2020-03-25 EP claimed
EP-2845845-B1 NOVEL OXIMESTER FLUORINE COMPOUND, AND PHOTOPOLYMERIZATION INITIATOR AND PHOTORESIST COMPOSITION COMPRISING SAME KOREA RES INST CHEMICAL TECH (KR) 2019-07-03 EP claimed
CN-111362801-A Propargyl tetrafluoropropionate monomer and synthesis method thereof 杭州师范大学 2020-07-03 CN disclosed
US-9664691-B2 Molecularly imprinted polymer for detection of pentraxin protein and method for preparing the same DAEGU GYEONGBUK INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 2017-05-30 US disclosed
US-8178727-B2 Bis(arylmethylidene)acetone compound, anti-cancer agent, carcinogenesis-preventive agent, inhibitor of expression of Ki-Ras, ErbB2, c-Myc and Cycline D1, β-catenin-degrading agent, and p53 expression enhancer NATIONAL UNIVERSITY CORPORATION TOHOKU UNIVERSITY (JP) 2012-05-15 US disclosed
US-20100152493-A1 BIS(ARYLMETHYLIDENE)ACETONE COMPOUND, ANTI-CANCER AGENT, CARCINOGENESIS-PREVENTIVE AGENT, INHIBITOR OF EXPRESSION OF Ki-Ras, ErbB2, c-Myc AND CYCLINE D1, BETA-CATENIN-DEGRADING AGENT, AND p53 EXPRESSION ENHANCER SHIBATA, HIROYUKI (JP) 2010-06-17 US disclosed
EP-1517881-A1 4-(3,3-DIHALO-ALLYLOXY)PHENOXY ALKYL DERIVATIVES Syngenta Participations AG (CH) 2005-03-30 EP disclosed
WO-2004002943-A1 4-(3,3-DIHALO-ALLYLOXY)PHENOXY ALKYL DERIVATIVES SYNGENTA PARTICIPATIONS AG (CH) 2004-01-08 WO disclosed
EP-0138750-B1 PROCESS FOR THE PRODUCTION OF SUBSTITUTED BENZIMIDAZOLES CIBA-GEIGY AG (CH) 1987-09-09 EP disclosed