Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 19/20 | 0.70 |
| ▸ | RARG | P13631 | 19/20 | 0.70 |
| ▸ | RARA | P10276 | 18/20 | 0.70 |
| ▸ | CYP26A1 | O43174 | 1/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.55 |
| ▸ | CRABP2 | P29373 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7637413 | 0.89 | RARB (0.70) | RARBRARGRARACYP26A1CYP3A4 | |
| SCHEMBL27462053 | 0.85 | RARA (0.53) | RARBRARGRARACYP26A1CYP3A4 | |
| SCHEMBL7642416 | 0.83 | RARB (0.71) | RARBRARGRARACYP26A1CYP3A4 | |
| SCHEMBL6236990 | 0.83 | RARB (1.00) | RARBRARGRARA | |
| SCHEMBL7800461 | 0.81 | RARB (0.61) | RARBRARGRARACYP26A1CYP3A4 | |
| SCHEMBL7640517 | 0.80 | RARB (0.67) | RARBRARGRARACYP26A1CYP3A4 | |
| SCHEMBL7806999 | 0.80 | RARA (0.78) | RARBRARGRARACYP26A1CYP3A4 | |
| SCHEMBL7157957 | 0.80 | RARB (0.72) | RARBRARGRARACYP26A1CYP3A4 | |
| SCHEMBL7637372 | 0.80 | RARA (0.61) | RARBRARGRARACYP26A1CYP3A4 | |
| SCHEMBL8901265 | 0.80 | RARB (0.63) | RARBRARGRARACYP26A1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1142928-C | Synthesis and use of retinoid compounds having negative hormone and/or antagonist activity | �ո��� | 2004-03-24 | — | — | CN | disclosed |
| CN-1121379-C | Synthesis and use of retinoid having negative hormone and/or antagonist activity | ALLERGAN CO (US) | 2003-09-17 | — | — | CN | disclosed |
| CN-1209802-A | Synthesis and use of retinoid having negative hormone and/or antagonist activity | ALLERGAN CO (US) | 1999-03-03 | — | — | CN | disclosed |