Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2744046 | 0.90 | TSHR (0.36) | TSHRALDH1A1THRB | |
| SCHEMBL2744772 | 0.86 | TSHR (0.38) | TSHRALDH1A1THRB | |
| SCHEMBL2744716 | 0.86 | TSHR (0.33) | TSHR | |
| SCHEMBL2744406 | 0.86 | TSHR (0.33) | TSHR | |
| SCHEMBL2744837 | 0.79 | TSHR (0.39) | TSHRALDH1A1 | |
| SCHEMBL2744855 | 0.79 | TSHR (0.39) | TSHRALDH1A1 | |
| SCHEMBL2744752 | 0.78 | TSHR (0.34) | TSHRALDH1A1 | |
| SCHEMBL2743688 | 0.77 | TSHR (0.39) | TSHR | |
| SCHEMBL10613414 | 0.77 | ALDH1A1 (0.39) | TSHRALDH1A1THRB | |
| SCHEMBL3298710 | 0.76 | TSHR (0.37) | TSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8178710-B2 | Silyl (meth)acrylate compound containing a siloxy group having a bulky substituent and its production method | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2012-05-15 | — | — | US | disclosed |
| US-20100105938-A1 | SILYL (METH)ACRYLATE COMPOUND CONTAINING A SILOXY GROUP HAVING A BULKY SUBSTITUENT AND ITS PRODUCTION METHOD | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2010-04-29 | — | — | US | disclosed |