Sugi Predict

Sugi Predict / Compounds / SCHEMBL2744309

SCHEMBL2744309

SCHEMBL2744309

C=C(C)C(=O)O[Si](O[Si](C)(O[Si](C)(C)C)O[Si](C)(C)C(C)(C)C)(C(C)C)C(C)C

nearest known ligand 0.30

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ TSHR P16473 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2744465 0.89 TSHR (0.36) TSHR
SCHEMBL2744532 0.88 TSHR (0.35) TSHR
SCHEMBL2744825 0.87 TSHR (0.30) TSHR
SCHEMBL2744396 0.86 TSHR (0.30) TSHR
SCHEMBL2744410 0.84 TSHR (0.36) TSHR
SCHEMBL2744836 0.82 — —
SCHEMBL2744837 0.81 TSHR (0.39) TSHR
SCHEMBL2744716 0.80 TSHR (0.33) TSHR
SCHEMBL2747701 0.77 ALDH1A1 (0.39) TSHR
SCHEMBL2744722 0.77 TSHR (0.36) TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8178710-B2 Silyl (meth)acrylate compound containing a siloxy group having a bulky substituent and its production method SHIN-ETSU CHEMICAL CO., LTD. (JP) 2012-05-15 — — US disclosed
EP-2182000-A1 Silyl (meth)acrylate compound containing a siloxy group having a bulky substituent and its production method Shin-Etsu Chemical Co., Ltd. (JP) 2010-05-05 — — EP disclosed
US-20100105938-A1 SILYL (METH)ACRYLATE COMPOUND CONTAINING A SILOXY GROUP HAVING A BULKY SUBSTITUENT AND ITS PRODUCTION METHOD SHIN-ETSU CHEMICAL CO., LTD. (JP) 2010-04-29 — — US disclosed