Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP2 | P11137 | 6/20 | 0.71 |
| ▸ | ATM | Q13315 | 2/20 | 0.66 |
| ▸ | MEN1 | O00255 | 2/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.64 |
| ▸ | MAPT | P10636 | 3/20 | 0.60 |
| ▸ | HPGD | P15428 | 2/20 | 0.60 |
| ▸ | POLB | P06746 | 1/20 | 0.60 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.60 |
| ▸ | XBP1 | P17861 | 1/20 | 0.60 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.60 |
| ▸ | GAA | P10253 | 1/20 | 0.57 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.57 |
| ▸ | CSF1R | P07333 | 2/20 | 0.52 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.52 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.52 |
| ▸ | LCK | P06239 | 1/20 | 0.52 |
| ▸ | PIM1 | P11309 | 1/20 | 0.52 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL42364 | 0.84 | MAP2 (1.00) | MAP2ATMMEN1KMT2AALDH1A1 | |
| SCHEMBL27464890 | 0.84 | MAP2 (0.70) | MAP2ATMMEN1KMT2AALDH1A1 | |
| SCHEMBL2716626 | 0.82 | MAP2 (0.81) | MAP2ATMMEN1KMT2AALDH1A1 | |
| SCHEMBL8686991 | 0.81 | MAP2 (1.00) | MAP2ATMMEN1KMT2AALDH1A1 | |
| SCHEMBL11403058 | 0.81 | MAP2 (1.00) | MAP2ALDH1A1KDM4EMAPTHPGD | |
| SCHEMBL8938266 | 0.78 | MAP2 (0.74) | MAP2ATMMEN1KMT2AALDH1A1 | |
| SCHEMBL4395807 | 0.76 | MAP2 (0.75) | MAP2ATMMEN1KMT2AALDH1A1 | |
| SCHEMBL28800459 | 0.75 | ALDH1A1 (1.00) | MAP2ATMMEN1KMT2AALDH1A1 | |
| SCHEMBL2715272 | 0.75 | ALDH1A1 (1.00) | MAP2ATMMEN1KMT2AALDH1A1 | |
| SCHEMBL4847744 | 0.75 | MAP2 (0.72) | MAP2ATMMEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1119856-A | Hiv reverse transcriptase inhibitors | MERCK & CO INC (US) | 1996-04-03 | — | — | CN | claimed |
| CN-1119856-A | Hiv reverse transcriptase inhibitors | MERCK & CO INC (US) | 1996-04-03 | — | — | CN | disclosed |