Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 4/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 5/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.41 |
| ▸ | MEN1 | O00255 | 4/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 3/20 | 0.40 |
| ▸ | HTT | P42858 | 3/20 | 0.40 |
| ▸ | USP2 | O75604 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27463409 | 0.83 | KMT2A (0.36) | MAPK1L3MBTL1ALDH1A1KMT2AMEN1 | |
| SCHEMBL27462472 | 0.82 | MAPK1 (0.43) | MAPK1L3MBTL1TDP1MAPTSMN1; SMN2 | |
| SCHEMBL27504042 | 0.78 | LMNA (0.44) | SMN1; SMN2ALDH1A1KMT2AMEN1KDM4E | |
| SCHEMBL27463407 | 0.78 | LMNA (0.44) | L3MBTL1TDP1MAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL27445303 | 0.77 | LMNA (0.44) | L3MBTL1SMN1; SMN2ALDH1A1KMT2AMEN1 | |
| SCHEMBL27462956 | 0.77 | LMNA (0.44) | L3MBTL1SMN1; SMN2ALDH1A1KMT2AMEN1 | |
| SCHEMBL27501667 | 0.75 | LMNA (0.42) | SMN1; SMN2ALDH1A1KMT2AKDM4ELMNA | |
| SCHEMBL27501665 | 0.73 | LMNA (0.43) | TDP1MAPTSMN1; SMN2ALDH1A1KMT2A | |
| Bromide SCHEMBL8087035 | 0.73 | KDM4E (0.44) | ALDH1A1KMT2AMEN1NPSR1KDM4E | |
| SCHEMBL27462962 | 0.73 | LMNA (0.39) | SMN1; SMN2ALDH1A1KDM4EPOLBHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1137886-C | 2,3-dioxo-1,2,3,4-tetrahydro-quinoyxalinyl derivatives | ��˹��ŵ�� | 2004-02-11 | — | — | CN | disclosed |
| CN-1193968-A | 2,3-dioxo-1,2,3,4-tetrahydro-quinoyxalinyl derivatives | NOVARTIS AG (CH) | 1998-09-23 | — | — | CN | disclosed |