Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARA | P10276 | 17/20 | 0.77 |
| ▸ | RARB | P10826 | 16/20 | 0.77 |
| ▸ | RARG | P13631 | 14/20 | 0.77 |
| ▸ | RXRA | P19793 | 1/20 | 0.77 |
| ▸ | NR2E1 | Q9Y466 | 1/20 | 0.77 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27445329 | 1.00 | RARA (0.77) | RARARARBRARGRXRANR2E1 | |
| SCHEMBL27445326 | 0.89 | RARB (0.64) | RARARARBRARGRXRANR2E1 | |
| SCHEMBL6238262 | 0.87 | RARB (0.83) | RARARARBRARGRXRANR2E1 | |
| SCHEMBL6238257 | 0.87 | RARB (0.83) | RARARARBRARGRXRANR2E1 | |
| SCHEMBL6755036 | 0.87 | RARA (1.00) | RARARARBRARGRXRANR2E1 | |
| SCHEMBL6755033 | 0.87 | RARA (1.00) | RARARARBRARGRXRANR2E1 | |
| SCHEMBL29613352 | 0.87 | RARA (1.00) | RARARARBRARGRXRANR2E1 | |
| SCHEMBL7628672 | 0.86 | RARA (0.81) | RARARARBRARGRXRANR2E1 | |
| SCHEMBL27509813 | 0.85 | RARB (0.56) | RARARARBRARGRXRANR2E1 | |
| SCHEMBL27444222 | 0.84 | RARB (0.83) | RARARARBRARGRXRANR2E1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1142928-C | Synthesis and use of retinoid compounds having negative hormone and/or antagonist activity | �ո��� | 2004-03-24 | — | — | CN | disclosed |
| CN-1121379-C | Synthesis and use of retinoid having negative hormone and/or antagonist activity | ALLERGAN CO (US) | 2003-09-17 | — | — | CN | disclosed |
| CN-1360890-A | Use of active retiene derivative with negative hormone and/or antagonist | ALLERGAN INC (US) | 2002-07-31 | — | — | CN | disclosed |
| CN-1209802-A | Synthesis and use of retinoid having negative hormone and/or antagonist activity | ALLERGAN CO (US) | 1999-03-03 | — | — | CN | disclosed |