Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | TOP2A | P11388 | 3/20 | 0.50 |
| ▸ | TOP2B | Q02880 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 1/20 | 0.49 |
| ▸ | CA2 | P00918 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | PIK3CG | P48736 | 3/20 | 0.46 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.46 |
| ▸ | PIK3R1 | P27986 | 2/20 | 0.46 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27445403 | 0.89 | KDM4E (0.55) | KDM4EALDH1A1TOP2ATOP2BLMNA | |
| SCHEMBL10591008 | 0.84 | TOP2A (0.59) | KDM4EALDH1A1TOP2ATOP2BLMNA | |
| SCHEMBL10590986 | 0.83 | TOP2A (0.56) | KDM4EALDH1A1TOP2ATOP2BLMNA | |
| SCHEMBL8194488 | 0.81 | TOP2A (0.67) | KDM4EALDH1A1TOP2ATOP2BLMNA | |
| SCHEMBL10590445 | 0.81 | TOP2A (0.53) | KDM4EALDH1A1TOP2ATOP2BLMNA | |
| SCHEMBL10589765 | 0.80 | PIK3CG (0.60) | KDM4EALDH1A1TOP2ATOP2BLMNA | |
| SCHEMBL27444467 | 0.80 | TOP2B (0.52) | KDM4EALDH1A1TOP2ATOP2BLMNA | |
| SCHEMBL27443718 | 0.78 | KDM4E (0.54) | KDM4EALDH1A1TOP2ATOP2BLMNA | |
| SCHEMBL27442712 | 0.78 | TOP2A (0.49) | KDM4EALDH1A1TOP2ATOP2BLMNA | |
| SCHEMBL27443095 | 0.78 | KDM4E (0.52) | KDM4EALDH1A1TOP2ATOP2BLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024138292-A1 | NOVEL PHENYLQUINOLONE COMPOUND HAVING ANTIBACTERIAL AND ANTICANCER FUNCTIONS, AND PREPARATION THEREOF | 深圳阿尔法分子科技有限责任公司 | 2024-07-04 | — | — | WO | disclosed |