Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | GFER | P55789 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.32 |
| ▸ | EIF4A3 | P38919 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27445415 | 0.78 | PDE7A (0.34) | HPGDGFERHSD17B10EIF4A3 | |
| SCHEMBL27445524 | 0.75 | HPGD (0.46) | HPGDGFERHSD17B10MAPKAPK2 | |
| SCHEMBL27445652 | 0.69 | HTR2A (0.30) | — | |
| SCHEMBL25781777 | 0.69 | MKNK2 (0.39) | HPGDGFERHSD17B10EIF4A3 | |
| SCHEMBL30926192 | 0.62 | RIPK3 (0.37) | — | |
| SCHEMBL27445651 | 0.61 | HTR2A (0.30) | — | |
| SCHEMBL24664743 | 0.61 | CYP3A4 (0.39) | HPGDGFERHSD17B10 | |
| SCHEMBL12219916 | 0.61 | GRM2 (0.41) | HPGDGFERHSD17B10EIF4A3 | |
| SCHEMBL32691381 | 0.61 | JAK2 (0.34) | — | |
| SCHEMBL11951609 | 0.60 | KARS1 (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024119122-A1 | CDK INHIBITORS AND METHODS AND USE THEREOF | RELAY THERAPEUTICS, INC. (US) | 2024-06-06 | — | — | WO | disclosed |