Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 7/20 | 0.58 |
| ▸ | MME | P08473 | 6/20 | 0.58 |
| ▸ | TACR1 | P25103 | 1/20 | 0.53 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.44 |
| ▸ | CASP1 | P29466 | 3/20 | 0.43 |
| ▸ | CASP3 | P42574 | 1/20 | 0.41 |
| ▸ | FNTA | P49354 | 1/20 | 0.41 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.41 |
| ▸ | MMP9 | P14780 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | PTGES | O14684 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8017737 | 0.96 | ACE (0.64) | ACEMMETACR1HRH4CASP1 | |
| SCHEMBL27547830 | 0.89 | TACR1 (0.57) | ACEMMETACR1HRH4CASP1 | |
| SCHEMBL27464096 | 0.87 | MME (0.68) | ACEMMETACR1HRH4CASP1 | |
| SCHEMBL8027462 | 0.86 | MME (0.77) | ACEMMEHRH4MMP9 | |
| SCHEMBL8027391 | 0.86 | MME (0.80) | ACEMMETACR1HRH4CASP1 | |
| SCHEMBL27446785 | 0.86 | MME (0.80) | ACEMMETACR1HRH4CASP1 | |
| SCHEMBL27462305 | 0.86 | ACE (0.47) | ACEMMETACR1 | |
| SCHEMBL27444751 | 0.85 | MME (0.55) | ACEMMETACR1HRH4CASP1 | |
| SCHEMBL27464501 | 0.85 | MME (0.68) | ACEMMETACR1HRH4CASP1 | |
| SCHEMBL8029478 | 0.85 | MME (0.59) | ACEMMETACR1HRH4CASP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1138321-A | 1, 3-dialkyl urea derivative with hydrocarbon group | SANTAN PHARMACEUTICAL CO LTD (JP) | 1996-12-18 | — | — | CN | disclosed |