Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 2/20 | 0.55 |
| ▸ | ACE | P12821 | 2/20 | 0.55 |
| ▸ | TACR1 | P25103 | 1/20 | 0.55 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.44 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.44 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.44 |
| ▸ | CASP3 | P42574 | 1/20 | 0.44 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.44 |
| ▸ | CPA1 | P15085 | 1/20 | 0.43 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.43 |
| ▸ | CASP1 | P29466 | 4/20 | 0.43 |
| ▸ | PSMB5 | P28074 | 2/20 | 0.42 |
| ▸ | MMP9 | P14780 | 2/20 | 0.42 |
| ▸ | REN | P00797 | 1/20 | 0.42 |
| ▸ | MMP8 | P22894 | 1/20 | 0.42 |
| ▸ | MMP14 | P50281 | 1/20 | 0.42 |
| ▸ | IL1RN | P18510 | 1/20 | 0.41 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.41 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.41 |
| ▸ | FNTA | P49354 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8028696 | 0.96 | MME (0.60) | MMEACETACR1OPRM1OPRD1 | |
| SCHEMBL27547830 | 0.88 | TACR1 (0.57) | MMEACETACR1CASP3HRH4 | |
| SCHEMBL27446259 | 0.86 | OPRM1 (0.45) | MMEACETACR1OPRM1OPRD1 | |
| SCHEMBL27445689 | 0.85 | ACE (0.58) | MMEACETACR1CASP3HRH4 | |
| SCHEMBL8030487 | 0.84 | ACE (0.74) | MMEACEOPRM1OPRD1OPRK1 | |
| SCHEMBL27464096 | 0.84 | MME (0.68) | MMEACETACR1CASP3HRH4 | |
| SCHEMBL8029478 | 0.84 | MME (0.59) | MMEACETACR1CASP3HRH4 | |
| SCHEMBL8027391 | 0.83 | MME (0.80) | MMEACETACR1CASP3HRH4 | |
| SCHEMBL27446785 | 0.83 | MME (0.80) | MMEACETACR1CASP3HRH4 | |
| SCHEMBL8027402 | 0.83 | ACE (0.48) | MMEACEOPRM1OPRD1OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1138321-A | 1, 3-dialkyl urea derivative with hydrocarbon group | SANTAN PHARMACEUTICAL CO LTD (JP) | 1996-12-18 | — | — | CN | disclosed |