Benzene

Benzene

SCHEMBL27445690

C=C(C#N)C#N.c1ccccc1

nearest known ligand 0.41

Full drug profile on Sugi Atlas →

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 0.41
ALDH1A1 P00352 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Benzene SCHEMBL27500610 0.96 TDP1 (0.39) TDP1ALDH1A1
SCHEMBL28774597 0.88 TDP1 (0.50) TDP1ALDH1A1
SCHEMBL136969 0.88
SCHEMBL28167750 0.84
Methane SCHEMBL28037662 0.84
SCHEMBL14353373 0.84
Biphenyl SCHEMBL591425 0.83 ALDH1A1 (0.47) TDP1ALDH1A1
Phenol SCHEMBL28319008 0.81 CA12 (0.55) TDP1ALDH1A1
Ethyne SCHEMBL28881511 0.80
Benzenethiol SCHEMBL10694695 0.79 ALDH1A1 (0.35) ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109020833-A A kind of synthetic method of the benzylidene malononitrile based on consecutive reaction 武汉绿帆世纪科技有限公司 2018-12-18 CN disclosed
CN-1120839-C Synthesis and application of 5,7-dihydroxy-4'-benzyloxyflavanone UNIV HUAZHONG (CN) 2003-09-10 CN disclosed
CN-1296948-A Synthesis and application of 5,7-dihydroxy-4'-benzyloxyflavanone UNIV HUAZHONG (CN) 2001-05-30 CN disclosed