Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | CFTR | P13569 | 1/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.47 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.47 |
| ▸ | GOPC | Q9HD26 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | KCNA5 | P22460 | 3/20 | 0.42 |
| ▸ | KCNN4 | O15554 | 2/20 | 0.42 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | NAMPT | P43490 | 1/20 | 0.41 |
| ▸ | TBXAS1 | P24557 | 3/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5147826 | 0.81 | SMN1; SMN2 (0.53) | NAPRTSMN1; SMN2CFTRSLC6A2SLC6A4 | |
| SCHEMBL2661850 | 0.79 | NAPRT (0.48) | NAPRTSMN1; SMN2CFTRSLC6A2SLC6A4 | |
| SCHEMBL28179698 | 0.79 | NAPRT (0.48) | NAPRTSMN1; SMN2CFTRSLC6A2SLC6A4 | |
| SCHEMBL28466253 | 0.77 | SRC (0.65) | NAPRTSMN1; SMN2CFTRSLC6A2SLC6A4 | |
| SCHEMBL771190 | 0.77 | KDM4E (0.46) | NAPRTSMN1; SMN2CFTRSLC6A2SLC6A4 | |
| SCHEMBL27445801 | 0.75 | SLC6A2 (0.38) | NAPRTSMN1; SMN2SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL27425068 | 0.75 | NAPRT (0.44) | NAPRTSMN1; SMN2CFTRSLC6A2SLC6A4 | |
| SCHEMBL2493545 | 0.74 | CFTR (0.58) | SMN1; SMN2CFTRSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL27390102 | 0.74 | SRC (0.56) | SMN1; SMN2LMNATSHR | |
| SCHEMBL27455320 | 0.74 | NAPRT (0.43) | NAPRTSMN1; SMN2CFTRSLC6A2SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1098716-A | Vasopressin antagonists and oxytocin antagonists | OTSUKA CHEMICAL CO LTD (JP) | 1995-02-15 | — | — | CN | disclosed |