SCHEMBL2744587

SCHEMBL2744587

CCCCCCCCCCCCCCCCCC(=O)Nc1cscc1NC(=O)CCCCCCCCCCCCCCCCC

nearest known ligand 0.56

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
CETP P11597 1/20 0.56
SOAT1 P35610 2/20 0.55
EP300 Q09472 1/20 0.54
PDE5A O76074 1/20 0.52
TDP1 Q9NUW8 2/20 0.51
LMNA P02545 2/20 0.51
POLB P06746 2/20 0.51
GAA P10253 2/20 0.51
DEGS1 O15121 1/20 0.51
L3MBTL1 Q9Y468 1/20 0.51
RAB9A P51151 3/20 0.50
KMT2A Q03164 2/20 0.50
HSP90AA1 P07900 1/20 0.50
FAAH O00519 1/20 0.48
ALDH1A1 P00352 2/20 0.48
HPGD P15428 1/20 0.48
SMN1; SMN2 Q16637 1/20 0.48
MEN1 O00255 1/20 0.48
MAPT P10636 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2744272 1.00 CETP (0.56) CETPSOAT1EP300PDE5ATDP1
SCHEMBL2744688 1.00 CETP (0.56) CETPSOAT1EP300PDE5ATDP1
SCHEMBL2744409 1.00 CETP (0.56) CETPSOAT1EP300PDE5ATDP1
SCHEMBL2745168 1.00 CETP (0.56) CETPSOAT1EP300PDE5ATDP1
SCHEMBL2745252 1.00 CETP (0.56) CETPSOAT1EP300PDE5ATDP1
SCHEMBL2745070 1.00 CETP (0.56) CETPSOAT1EP300PDE5ATDP1
SCHEMBL2744275 1.00 CETP (0.56) CETPSOAT1EP300PDE5ATDP1
SCHEMBL2745420 1.00 CETP (0.56) CETPSOAT1EP300PDE5ATDP1
SCHEMBL16307251 0.89 RAB9A (0.51) CETPSOAT1EP300PDE5ATDP1
SCHEMBL15708854 0.83 CETP (0.61) CETPSOAT1EP300TDP1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7321012-B2 Method of crosslinking intrinsically conductive polymers or intrinsically conductive polymer precursors and the articles obtained therefrom THE UNIVERSITY OF CONNECTICUT (US) 2008-01-22 US claimed
WO-2005014693-A1 METHOD OF CROSSLINKING INTRINSICALLY CONDUCTIVE POLYMERS OR INTRINSICALLY CONDUCTIVE POLYMER PRECURSORS AND THE ARTICLES OBTAINED THEREFROM UNIVERSITY OF CONNECTICUT (US) 2005-02-17 WO claimed
US-20040242792-A1 Method of crosslinking intrinsically conductive polymers or intrinsically conductive polymer precursors and the articles obtained therefrom CONNECTICUT, THE UNIVERSITY OF 2004-12-02 US claimed
US-20120196078-A1 CONJUGATED POLYMER FIBER, PREPARATION AND USE THEREOF SOTZING GREGORY A (US) 2012-08-02 US disclosed
US-8178629-B2 Conjugated polymer fiber, preparation and use thereof UNIVERSITY OF CONNECTICUT (US) 2012-05-15 US disclosed
US-7321012-B2 Method of crosslinking intrinsically conductive polymers or intrinsically conductive polymer precursors and the articles obtained therefrom THE UNIVERSITY OF CONNECTICUT (US) 2008-01-22 US disclosed
US-20070089845-A1 Conjugated polymer fiber, preparation and use thereof UNIVERSITY OF CONNECTICUT 2007-04-26 US disclosed
WO-2006084088-A1 CONJUGATED POLYMER FIBER, PREPARATION AND USE THEREOF UNIVERSITY OF CONNECTICUT (US) 2006-08-10 WO disclosed
WO-2005014693-A1 METHOD OF CROSSLINKING INTRINSICALLY CONDUCTIVE POLYMERS OR INTRINSICALLY CONDUCTIVE POLYMER PRECURSORS AND THE ARTICLES OBTAINED THEREFROM UNIVERSITY OF CONNECTICUT (US) 2005-02-17 WO disclosed
US-20040242792-A1 Method of crosslinking intrinsically conductive polymers or intrinsically conductive polymer precursors and the articles obtained therefrom CONNECTICUT, THE UNIVERSITY OF 2004-12-02 US disclosed
US-6242561-B1 USED AS SEMICONDUCTORS; ELECTROCHROMIC AND ANTISTATIC PROPERTIES BASF AKTIENGESELLSCHAFT (DE) 2001-06-05 US disclosed