Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | LTA4H | P09960 | 2/20 | 0.41 |
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.41 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | DHFR | P00374 | 1/20 | 0.39 |
| ▸ | CDC7 | O00311 | 1/20 | 0.39 |
| ▸ | PLK4 | O00444 | 1/20 | 0.39 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.39 |
| ▸ | CHUK | O15111 | 1/20 | 0.39 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.39 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.39 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.39 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.39 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.39 |
| ▸ | PAK4 | O96013 | 1/20 | 0.39 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Biphenyl SCHEMBL27599273 | 0.96 | TSHR (0.55) | TSHRALDH1A1PTPN1TDP1LTA4H | |
| Biphenyl SCHEMBL28132699 | 0.93 | TSHR (0.52) | TSHRALDH1A1PTPN1TDP1LTA4H | |
| Biphenyl SCHEMBL28541047 | 0.93 | TSHR (0.59) | TSHRALDH1A1PTPN1TDP1LTA4H | |
| Biphenyl SCHEMBL27934538 | 0.89 | TSHR (0.55) | TSHRALDH1A1PTPN1TDP1LTA4H | |
| SCHEMBL28694266 | 0.84 | TSHR (0.63) | TSHRALDH1A1TDP1 | |
| Biphenyl SCHEMBL15347228 | 0.83 | ALDH1A1 (0.56) | TSHRALDH1A1LTA4HTLR8GPR84 | |
| Biphenyl SCHEMBL5868587 | 0.81 | ALDH1A1 (0.53) | TSHRALDH1A1GPR84MAPK1 | |
| Hexadecane SCHEMBL8524813 | 0.81 | ALDH1A1 (0.53) | TSHRALDH1A1GPR84MAPK1 | |
| Dodecane SCHEMBL27916009 | 0.81 | ALDH1A1 (0.53) | TSHRALDH1A1GPR84MAPK1 | |
| Biphenyl SCHEMBL27853080 | 0.81 | ALDH1A1 (0.53) | TSHRALDH1A1GPR84MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101113137-B | Intermidiate for preparing 1,2-oxygen nitrogen heterocyclic-2-alkene acylbenzene and its preparation | BASF AG | 2010-12-29 | — | — | CN | disclosed |
| CN-100516030-C | Intermidiate for preparing 1,2-oxygen nitrogen heterocyclic-2-alkene acylbenzene and its preparation | BASF AG (DE) | 2009-07-22 | — | — | CN | disclosed |
| CN-101113137-A | Intermidiate for preparing 1,2-oxygen nitrogen heterocyclic-2-alkene acylbenzene and its preparation | BASF AG (DE) | 2008-01-30 | — | — | CN | disclosed |
| CN-1255377-C | Intermediate for preparing isoxazoline-3-yl acyl benzene and process for preparing intermediate | BASF AG (DE) | 2006-05-10 | — | — | CN | disclosed |
| CN-1757634-A | Intermidiate for preparing 1,2-oxygen nitrogen heterocyclic-2-alkene acylbenzene and its preparation | BASF AG (DE) | 2006-04-12 | — | — | CN | disclosed |
| CN-1495158-A | Intermediate for preparing isoxazoline-3-yl acyl benzene and process for preparing intermediate | �����ɷ� | 2004-05-12 | — | — | CN | disclosed |
| CN-1139578-C | Preparation of isoxazolin-3-yl-acylbenzenes | �����ɷ� | 2004-02-25 | — | — | CN | disclosed |
| CN-1300284-A | Preparation of isoxazolin-3-yl-acylbenzenes | BASF AG (DE) | 2001-06-20 | — | — | CN | disclosed |