Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.58 |
| ▸ | CA2 | P00918 | 2/20 | 0.56 |
| ▸ | CA12 | O43570 | 1/20 | 0.56 |
| ▸ | CA1 | P00915 | 1/20 | 0.56 |
| ▸ | CA9 | Q16790 | 1/20 | 0.56 |
| ▸ | ACLY | P53396 | 1/20 | 0.55 |
| ▸ | THRA | P10827 | 3/20 | 0.54 |
| ▸ | THRB | P10828 | 3/20 | 0.54 |
| ▸ | ESR1 | P03372 | 2/20 | 0.53 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.53 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.53 |
| ▸ | TACR2 | P21452 | 2/20 | 0.53 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.53 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.53 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | SHBG | P04278 | 1/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14381415 | 1.00 | HPGD (0.58) | HPGDCA2CA12CA1CA9 | |
| SCHEMBL27277839 | 0.93 | HPGD (0.66) | HPGDCA2CA12CA1CA9 | |
| SCHEMBL16976564 | 0.85 | KDM4E (0.65) | HPGDCA2CA12CA1CA9 | |
| SCHEMBL11781069 | 0.81 | CA2 (0.62) | HPGDCA2CA12CA1CA9 | |
| SCHEMBL7151939 | 0.80 | FFAR1 (0.78) | HPGDCA2KDM4ECYP3A4HTR2C | |
| SCHEMBL16249739 | 0.80 | HPGD (0.54) | HPGDCA2CA12CA1CA9 | |
| SCHEMBL4982618 | 0.80 | CA12 (0.59) | CA2CA12CA1CA9THRA | |
| SCHEMBL11027242 | 0.78 | FFAR1 (0.66) | ALDH1A1LMNAADRB3FFAR1FFAR4 | |
| SCHEMBL23752204 | 0.78 | HPGD (0.61) | HPGDKDM4EALDH1A1LMNATP53 | |
| SCHEMBL27870616 | 0.77 | MEN1 (0.62) | HPGDESR1ADRA2AADORA3TACR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1100425-A | Thiazolopyrimidine derivatives | DAIICHI SEIYAKU CO (JP) | 1995-03-22 | — | — | CN | disclosed |