SCHEMBL27446830

SCHEMBL27446830

CC(C(=O)O)c1cccnc1.[LiH]

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AKR1C3 P42330 1/20 0.56
AKR1C2 P52895 1/20 0.56
SMN1; SMN2 Q16637 4/20 0.52
CFTR P13569 1/20 0.50
SLC6A2 P23975 1/20 0.50
SLC6A4 P31645 1/20 0.50
SLC6A3 Q01959 1/20 0.50
GOPC Q9HD26 1/20 0.50
CYP17A1 P05093 1/20 0.50
CYP19A1 P11511 1/20 0.50
TBXAS1 P24557 4/20 0.49
KDM4E B2RXH2 2/20 0.49
PTGS1 P23219 3/20 0.47
PTGS2 P35354 3/20 0.47
ALDH1A1 P00352 2/20 0.46
APP P05067 1/20 0.46
GAA P10253 1/20 0.46
HCAR3 P49019 1/20 0.46
HCAR2 Q8TDS4 1/20 0.46
LMNA P02545 2/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL575045 0.98 AKR1C3 (0.57) AKR1C3AKR1C2SMN1; SMN2CFTRSLC6A2
SCHEMBL6259017 0.98 AKR1C3 (0.57) AKR1C3AKR1C2SMN1; SMN2CFTRSLC6A2
Hydrochloric Acid SCHEMBL4076278 0.96 AKR1C3 (0.56) AKR1C3AKR1C2SMN1; SMN2CFTRSLC6A2
SCHEMBL22899009 0.87 CYP19A1 (0.51) AKR1C3AKR1C2SMN1; SMN2CFTRSLC6A2
SCHEMBL27492286 0.85 CYP19A1 (0.52) AKR1C3AKR1C2SMN1; SMN2CFTRSLC6A2
Pyridine SCHEMBL28233602 0.84 SMN1; SMN2 (0.50) AKR1C3AKR1C2SMN1; SMN2CFTRSLC6A2
SCHEMBL9484991 0.82 NAPRT (0.53) AKR1C3AKR1C2SMN1; SMN2CYP19A1TBXAS1
SCHEMBL17233832 0.81 CYP17A1 (0.50) SMN1; SMN2CFTRSLC6A2SLC6A4SLC6A3
SCHEMBL30159419 0.81 CYP17A1 (0.50) SMN1; SMN2CFTRSLC6A2SLC6A4SLC6A3
SCHEMBL17233924 0.81 CYP17A1 (0.50) SMN1; SMN2CFTRSLC6A2SLC6A4SLC6A3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1117628-C Bimetallic catalyst for homogeneous methanol carbonylation and its prepn CHINESE ACAD INST CHEMISTRY (CN) 2003-08-13 CN claimed
CN-1349855-A Bimetallic catalyst for homogeneous methanol carbonylation and its prepn CHINESE ACAD INST CHEMISTRY (CN) 2002-05-22 CN claimed
CN-103038206-A Carbonylation process CELANESE INTERNALTIONAL CORP 2013-04-10 CN disclosed
CN-102471209-A Acetic acid production by carbonylation with enhanced reaction and flash CELANESE INT CORP (US) 2012-05-23 CN disclosed
CN-1117628-C Bimetallic catalyst for homogeneous methanol carbonylation and its prepn CHINESE ACAD INST CHEMISTRY (CN) 2003-08-13 CN disclosed
CN-1349855-A Bimetallic catalyst for homogeneous methanol carbonylation and its prepn CHINESE ACAD INST CHEMISTRY (CN) 2002-05-22 CN disclosed