SCHEMBL6259017

SCHEMBL6259017

CC(C(=O)O)c1cccnc1

nearest known ligand 0.70

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AKR1C3 P42330 1/20 0.57
AKR1C2 P52895 1/20 0.57
SMN1; SMN2 Q16637 4/20 0.53
CFTR P13569 1/20 0.52
SLC6A2 P23975 1/20 0.52
SLC6A4 P31645 1/20 0.52
SLC6A3 Q01959 1/20 0.52
GOPC Q9HD26 1/20 0.52
CYP17A1 P05093 1/20 0.51
CYP19A1 P11511 1/20 0.51
TBXAS1 P24557 4/20 0.50
KDM4E B2RXH2 2/20 0.50
PTGS2 P35354 3/20 0.48
ALDH1A1 P00352 2/20 0.47
APP P05067 1/20 0.47
GAA P10253 1/20 0.47
HCAR3 P49019 1/20 0.47
HCAR2 Q8TDS4 1/20 0.47
LMNA P02545 2/20 0.46
L3MBTL1 Q9Y468 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL575045 1.00 AKR1C3 (0.57) AKR1C3AKR1C2SMN1; SMN2CFTRSLC6A2
SCHEMBL27446830 0.98 AKR1C3 (0.56) AKR1C3AKR1C2SMN1; SMN2CFTRSLC6A2
Hydrochloric Acid SCHEMBL4076278 0.98 AKR1C3 (0.56) AKR1C3AKR1C2SMN1; SMN2CFTRSLC6A2
SCHEMBL22899009 0.89 CYP19A1 (0.51) AKR1C3AKR1C2SMN1; SMN2CFTRSLC6A2
SCHEMBL27492286 0.86 CYP19A1 (0.52) AKR1C3AKR1C2SMN1; SMN2CFTRSLC6A2
Pyridine SCHEMBL28233602 0.85 SMN1; SMN2 (0.50) AKR1C3AKR1C2SMN1; SMN2CFTRSLC6A2
SCHEMBL9484991 0.84 NAPRT (0.53) AKR1C3AKR1C2SMN1; SMN2CYP19A1TBXAS1
SCHEMBL17233832 0.83 CYP17A1 (0.50) SMN1; SMN2CFTRSLC6A2SLC6A4SLC6A3
SCHEMBL30159419 0.83 CYP17A1 (0.50) SMN1; SMN2CFTRSLC6A2SLC6A4SLC6A3
SCHEMBL17233924 0.83 CYP17A1 (0.50) SMN1; SMN2CFTRSLC6A2SLC6A4SLC6A3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 64 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1212197-C Catalytic system used for homogeneous hydroxylation reaction and its manufacturing method and application CHINESE ACAD INST CHEMISTRY (CN) 2005-07-27 CN claimed
WO-2004089357-A2 ANTI-FUNGAL FORMULATION OF TRITERPENE AND ESSENTIAL OIL REGENTS OF THE UNIVERSITY OF MINNESOTA (US) 2004-10-21 WO claimed
CN-1517150-A Catalytic system used for homogeneous hydroxylation reaction and its manufacturing method and application 中国科学院化学研究所 2004-08-04 CN claimed
US-20260022143-A1 Cyclic Peptide Inhibitors of IL-23 JANSSEN PHARMACEUTICA NV (BE) 2026-01-22 US disclosed
CN-120035578-A Sulfonamide compound, preparation method and medical application thereof 深圳信立泰药业股份有限公司 2025-05-23 CN disclosed
CN-119751456-A Spiro compounds C4医药公司 2025-04-04 CN disclosed
WO-2025072539-A1 AMINO ACID COMPOUNDS WITH NITROGEN LINKERS AND USES THEREOF PLIANT THERAPEUTICS, INC. (US) 2025-04-03 WO disclosed
CN-112312904-B Spiro compounds C4医药公司 2025-01-07 CN disclosed
US-20240425528-A1 AROMATIC BORON-CONTAINING COMPOUNDS AND RELATED INSULIN ANALOGS PROTOMER TECH INC (US) 2024-12-26 US disclosed
WO-2024240056-A1 SULFONAMIDE COMPOUND, PREPARATION METHOD THEREFOR, AND PHARMACEUTICAL USE THEREOF 深圳信立泰药业股份有限公司 2024-11-28 WO disclosed
US-12139502-B2 Aromatic boron-containing compounds and related insulin analogs PROTOMER TECHNOLOGIES INC. (US) 2024-11-12 US disclosed
CN-1212197-C Catalytic system used for homogeneous hydroxylation reaction and its manufacturing method and application CHINESE ACAD INST CHEMISTRY (CN) 2005-07-27 CN disclosed
WO-2004089357-A2 ANTI-FUNGAL FORMULATION OF TRITERPENE AND ESSENTIAL OIL REGENTS OF THE UNIVERSITY OF MINNESOTA (US) 2004-10-21 WO disclosed
CN-1517150-A Catalytic system used for homogeneous hydroxylation reaction and its manufacturing method and application 中国科学院化学研究所 2004-08-04 CN disclosed
CN-1085980-C Meta-guanidino, ureido, thioureido or azacyclic aminobenzoic acid derivatives as integrin antagonists SEARLE & CO (US) 2002-06-05 CN disclosed
CN-1042031-C Novel quaternary nitrogen-containing phosphonate compounds, pharmaceutical compositions, and methods of treating abnormal calcium and phosphate metabolism and methods of treating and preventing dental PROCTER & GAMBLE PHARMA (US) 1999-02-10 CN disclosed
CN-1201454-A Meta-guanidino, ureido, thioureido or azacyclic aminobenzoic acid derivatives as integrin antagonists SEARLE & CO (US) 1998-12-09 CN disclosed
CN-1130898-A Difluorostone antiviral analogs MERRELL DOW PHARMA (US) 1996-09-11 CN disclosed
CN-1126988-A Difluoro statone analogs MERRELL DOW PHARMA (US) 1996-07-17 CN disclosed
CN-1088213-A Contain the quaternary nitrogen phosphinic acid compounds, pharmaceutical composition and treatment calcium and the unusual method of phosphate metabolism and treatment prevention tartar and dental plaque method PROCTER & GAMBLE PHARMA (US) 1994-06-22 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260022143-A1 Cyclic Peptide Inhibitors of IL-23 IL23R, IL17A, IL36G AKR1C3 1618/4885AKR1C2 2274/4885SMN1; SMN2 2640/4885
US-20240425528-A1 AROMATIC BORON-CONTAINING COMPOUNDS AND RELATED INSULIN ANALOGS IAPP, GPR119, INSR AKR1C3 1171/4885AKR1C2 851/4885SMN1; SMN2 775/4885
US-12139502-B2 Aromatic boron-containing compounds and related insulin analogs IAPP, GPR119, INSR AKR1C3 1171/4885AKR1C2 851/4885SMN1; SMN2 775/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.