Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES1 | P23141 | 9/20 | 0.47 |
| ▸ | CES2 | O00748 | 6/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | SRC | P12931 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.41 |
| ▸ | HTR1A | P08908 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | SCN1A | P35498 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.41 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.41 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5321540 | 0.89 | CES1 (0.49) | CES1CES2LMNASRCALDH1A1 | |
| SCHEMBL28442493 | 0.84 | CES1 (0.47) | CES1CES2LMNASRCTDP1 | |
| SCHEMBL8462267 | 0.83 | CES1 (0.50) | CES1CES2LMNASRCTDP1 | |
| SCHEMBL9617688 | 0.82 | SRC (0.46) | CES1CES2LMNASRCTDP1 | |
| SCHEMBL10607551 | 0.82 | CES1 (0.46) | CES1CES2LMNATDP1MAPT | |
| SCHEMBL16062609 | 0.81 | TSHR (0.46) | LMNATDP1CYP2D6SCN1ASCN2A | |
| SCHEMBL3128812 | 0.81 | CES1 (0.44) | CES1CES2LMNASRCTDP1 | |
| SCHEMBL10471882 | 0.80 | SRC (0.47) | CES1CES2LMNASRCTDP1 | |
| SCHEMBL10458191 | 0.80 | GAA (0.53) | CES1CES2LMNASRCTDP1 | |
| SCHEMBL4808857 | 0.80 | CES1 (0.47) | CES1CES2LMNASRCTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1138743-C | 1, 3-diketone compound | ض� | 2004-02-18 | — | — | CN | disclosed |
| CN-1054139-C | Catalyst component for the polymerization of olefins and catalyst obtained | MONTELL NORTH AMERICAN INC (US) | 2000-07-05 | — | — | CN | disclosed |
| CN-1257061-A | 1, 3-diketone compound | MONTELL NORTH AMERICAN INC (US) | 2000-06-21 | — | — | CN | disclosed |
| CN-1105671-A | Components and catalysts for olefin polymerization | HIMONT INC (US) | 1995-07-26 | — | — | CN | disclosed |