Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 3/20 | 0.37 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.37 |
| ▸ | PRSS2 | P07478 | 3/20 | 0.37 |
| ▸ | PRSS3 | P35030 | 3/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | MMP1 | P03956 | 1/20 | 0.36 |
| ▸ | MMP2 | P08253 | 1/20 | 0.36 |
| ▸ | MMP9 | P14780 | 1/20 | 0.36 |
| ▸ | MMP8 | P22894 | 1/20 | 0.36 |
| ▸ | MMP13 | P45452 | 1/20 | 0.36 |
| ▸ | RAPGEF4 | Q8WZA2 | 5/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.31 |
| ▸ | GAA | P10253 | 3/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | BRD4 | O60885 | 1/20 | 0.31 |
| ▸ | PTGES | O14684 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18700928 | 0.83 | F2 (0.41) | F2PRSS1PRSS2PRSS3CA1 | |
| SCHEMBL27357250 | 0.81 | KDM4E (0.52) | F2PRSS1PRSS2PRSS3CA1 | |
| SCHEMBL2884819 | 0.74 | CA1 (0.42) | F2PRSS1PRSS2PRSS3CA1 | |
| SCHEMBL7707792 | 0.72 | CA1 (0.50) | F2PRSS1PRSS2PRSS3CA1 | |
| SCHEMBL27452470 | 0.72 | LCK (0.39) | ALDH1A1GAALMNACASP6TDP1 | |
| SCHEMBL8365909 | 0.72 | ALDH1A1 (0.50) | F2PRSS1PRSS2PRSS3CA1 | |
| SCHEMBL11746428 | 0.72 | CA1 (0.41) | F2PRSS1PRSS2PRSS3CA1 | |
| SCHEMBL1364945 | 0.71 | KDM4E (0.52) | F2PRSS1PRSS2PRSS3CA1 | |
| SCHEMBL29633914 | 0.71 | KDM4E (0.52) | F2PRSS1PRSS2PRSS3CA1 | |
| SCHEMBL2059007 | 0.71 | CA1 (0.39) | F2PRSS1PRSS2PRSS3CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1071540-C | Stabilization of aqueous 3-isothiazolone solutions | ROHM & HAAS (US) | 2001-09-26 | — | — | CN | disclosed |
| CN-1140542-A | Stabilization of aqueous 3-isothiazolone solutions | ROHM & HAAS (US) | 1997-01-22 | — | — | CN | disclosed |