SCHEMBL27447355

SCHEMBL27447355

Clc1ccc2[nH]nnc2c1-c1ccccc1

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AKT2 P31751 3/20 0.37
CHEK1 O14757 1/20 0.37
MAP2 P11137 2/20 0.35
METAP2 P50579 1/20 0.34
HPGD P15428 2/20 0.33
CSF1R P07333 1/20 0.33
GRIN2D O15399 1/20 0.33
GRIN3B O60391 1/20 0.33
GRIN1 Q05586 1/20 0.33
GRIN2A Q12879 1/20 0.33
GRIN2B Q13224 1/20 0.33
GRIN2C Q14957 1/20 0.33
GRIN3A Q8TCU5 1/20 0.33
SMARCA2 P51531 1/20 0.33
SMARCA4 P51532 1/20 0.33
PBRM1 Q86U86 1/20 0.33
MAPK1 P28482 1/20 0.33
NPSR1 Q6W5P4 1/20 0.33
AKT1 P31749 1/20 0.32
NPC1 O15118 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27412736 0.81 AKT2 (0.38) AKT2CHEK1METAP2SMARCA2SMARCA4
SCHEMBL80394 0.79 CHEK1 (0.37) AKT2CHEK1CSF1RGRIN2DGRIN3B
SCHEMBL29359068 0.79 CHEK1 (0.37) AKT2CHEK1CSF1RGRIN2DGRIN3B
SCHEMBL1462356 0.79 AKT2 (0.44) AKT2CHEK1HPGDSMARCA2SMARCA4
SCHEMBL9632559 0.79 MAPK1 (0.40) AKT2CHEK1HPGDCSF1RSMARCA2
SCHEMBL29421033 0.79 AKT2 (0.44) AKT2CHEK1HPGDSMARCA2SMARCA4
SCHEMBL7129918 0.79 ESR2 (0.44) HPGDMAPK1NPSR1TP53CYP1A2
SCHEMBL6897857 0.78 CHEK1 (0.36) AKT2CHEK1CSF1RGRIN2DGRIN3B
SCHEMBL8836008 0.78 CHEK1 (0.36) AKT2CHEK1CSF1RGRIN2DGRIN3B
SCHEMBL7645989 0.78 GAA (0.38) MAP2HPGDNPSR1NPC1CYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1072695-A Additive system of dispersible solid form and preparation method thereof in water-bearing media EASTMAN KODAK CO (US) 1993-06-02 CN claimed
CN-1840328-B Antistatic decorative slice for suppressing bend whitening DAINIPPON PRINTING CO LTD 2011-04-06 CN disclosed
CN-1840328-A Antistatic decorative slice for suppressing bend whitening DAINIPPON PRINTING CO LTD (JP) 2006-10-04 CN disclosed
CN-1072695-A Additive system of dispersible solid form and preparation method thereof in water-bearing media EASTMAN KODAK CO (US) 1993-06-02 CN disclosed