SCHEMBL7645989

SCHEMBL7645989

Cc1ccccc1-c1c(Cl)ccc2[nH]nnc12

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 2/20 0.38
MGAM O43451 1/20 0.38
SI P14410 1/20 0.38
MGAM2 Q2M2H8 1/20 0.38
TRPA1 O75762 1/20 0.36
MAP2 P11137 1/20 0.36
NPC1 O15118 3/20 0.35
RAB9A P51151 3/20 0.35
SMN1; SMN2 Q16637 2/20 0.35
CASP3 P42574 1/20 0.35
SENP8 Q96LD8 1/20 0.35
SENP7 Q9BQF6 1/20 0.35
SENP6 Q9GZR1 1/20 0.35
POLB P06746 1/20 0.34
KMT2A Q03164 1/20 0.34
HPGD P15428 2/20 0.34
TSHR P16473 1/20 0.34
HSD17B10 Q99714 1/20 0.34
ALDH1A1 P00352 3/20 0.33
NPSR1 Q6W5P4 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27730173 0.86 MGAM (0.35) GAAMGAMSIMGAM2TRPA1
SCHEMBL28596106 0.84 GAA (0.40) GAATRPA1MAP2NPC1RAB9A
SCHEMBL28106755 0.82 TRPA1 (0.41) TRPA1HSD11B1
SCHEMBL31625576 0.82 HPGD (0.39) GAAMGAMSIMGAM2TRPA1
SCHEMBL30117209 0.82 MEN1 (0.39) GAAMGAMSIMGAM2NPC1
SCHEMBL504322 0.82 HPGD (0.39) GAAMGAMSIMGAM2TRPA1
SCHEMBL6064915 0.82 MEN1 (0.39) GAAMGAMSIMGAM2NPC1
SCHEMBL27447355 0.78 AKT2 (0.37) MAP2NPC1RAB9ASMN1; SMN2KMT2A
SCHEMBL28674437 0.77 GAA (0.35) GAATRPA1NPC1RAB9ASMN1; SMN2
SCHEMBL11343970 0.77 HSD11B1 (0.34) SMN1; SMN2HPGDALDH1A1NPSR1HSD11B1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115066457-A Crosslinkable polysiloxanes 联邦科学和工业研究组织 2022-09-16 CN disclosed
CN-101263171-B Block copolymer and method for producing heat shrinkable film ASAHI CHEMICAL CORP 2015-07-08 CN disclosed
CN-103642167-A Process for production of heat shrinkable film ASAHI KASEI CHEMICALS CORP 2014-03-19 CN disclosed
CN-101208362-B Process for producing cycloolefinic resin composition, and cycloolefinic resin composition MITSUI CHEMICALS INC 2012-12-12 CN disclosed
CN-100558812-C Resin composition and use thereof MITSUI CHEMICALS INC (JP) 2009-11-11 CN disclosed
CN-100471908-C Heat shrinkable film comprising a polymer composition ASAHI CHEMICAL IND (JP) 2009-03-25 CN disclosed
CN-101263171-A Block copolymer and method for producing heat shrinkable film ASAHI CHEMICAL CORP (JP) 2008-09-10 CN disclosed
CN-101208362-A Process for producing cycloolefinic resin composition, and cycloolefinic resin composition MITSUI CHEMICALS INC (JP) 2008-06-25 CN disclosed
CN-1984933-A Thermoplastic resin MITSUI CHEMICALS INC (JP) 2007-06-20 CN disclosed
CN-1984956-A Resin composition and use thereof MITSUI CHEMICALS INC (JP) 2007-06-20 CN disclosed
CN-1898319-A Heat shrink film from polymer composition ASAHI CHEMICAL CORP (JP) 2007-01-17 CN disclosed
EP-1242536-A2 CHLORINATED POLYOLEFIN RESIN COMPOSITION Showa Denko K.K. (JP) 2002-09-25 EP disclosed
WO-2002016487-A2 CHLORINATED POLYOLEFIN RESIN COMPOSITION SHOWA DENKO K.K. (JP) 2002-02-28 WO disclosed
EP-0866835-A1 COMPOSITION COMPRISING A PLASTIC AND AN ADDITIVE DENDRIMER COMBINATION DSM N.V. (NL) 1998-09-30 EP disclosed
WO-1997019987-A1 COMPOSITION COMPRISING A PLASTIC AND AN ADDITIVE DENDRIMER COMBINATION DSM N.V. (NL) 1997-06-05 WO disclosed