Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 1/20 | 0.50 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | TP53 | P04637 | 2/20 | 0.44 |
| ▸ | S1PR2 | O95136 | 2/20 | 0.44 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | XBP1 | P17861 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Fluoride SCHEMBL11759407 | 1.00 | — | — | |
| Fluoride SCHEMBL27460461 | 0.97 | APP (0.48) | APPEPHX2LMNATP53S1PR2 | |
| Fluoride SCHEMBL27813553 | 0.97 | APP (0.48) | APPEPHX2LMNATP53S1PR2 | |
| Fluoride SCHEMBL28021334 | 0.97 | APP (0.48) | APPEPHX2LMNATP53S1PR2 | |
| Fluoride SCHEMBL27590430 | 0.97 | APP (0.48) | APPEPHX2LMNATP53S1PR2 | |
| Fluoride SCHEMBL27883105 | 0.97 | APP (0.48) | APPEPHX2LMNATP53S1PR2 | |
| Hydrochloric Acid SCHEMBL28099472 | 0.97 | APP (0.48) | APPEPHX2LMNATP53S1PR2 | |
| Bromide SCHEMBL28848302 | 0.97 | APP (0.48) | APPEPHX2LMNATP53S1PR2 | |
| Fluoride SCHEMBL28255739 | 0.97 | APP (0.48) | APPEPHX2LMNATP53S1PR2 | |
| SCHEMBL10012319 | 0.97 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 79 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103038212-B | Process for preparation of 3-substituted-4-fluoropyrrolidine derivatives | KYORIN SEIYAKU KK | 2015-04-22 | — | — | CN | claimed |
| CN-102105442-B | Aqueous methods for making fluorinated sulfonate esters | 3M INNOVATIVE PROPERTIES CO | 2014-08-06 | — | — | CN | claimed |
| CN-103038212-A | Process for preparation of 3-substituted-4-fluoropyrrolidine derivatives | KYORIN SEIYAKU KK | 2013-04-10 | — | — | CN | claimed |
| CN-101528721-B | Process for the preparation of (s)-4-fluoromethyl-dihydro-furan-2-one | HOFFMANN LA ROCHE | 2013-01-02 | — | — | CN | claimed |
| CN-101323597-B | Preparation of 4-(4-fluorophenyl)-6-isopropyl-2-(N-methyl-N-methylsulfonyl amido) pyrimidine-5-formaldehyde | ANHUI QINGYUN PHARMACEUTICAL AND CHEMICAL CO LTD | 2012-09-05 | — | — | CN | claimed |
| CN-101578254-A | Process for producing optically active alpha-fluorocarboxylic acid ester | CENTRAL GLASS CO LTD (JP) | 2009-11-11 | — | — | CN | claimed |
| CN-101528721-A | Process for the preparation of (S)-4-fluoromethyl-dihydro-furan-2-one | HOFFMANN LA ROCHE (CH) | 2009-09-09 | — | — | CN | claimed |
| CN-101323597-A | Preparation of 4-(4-fluorophenyl)-6-isopropyl-2-(N-methyl-N-methylsulfonyl amido) pyrimidine-5-formaldehyde | ANHUI QINGYUN PHARMACEUTICAL A (CN) | 2008-12-17 | — | — | CN | claimed |
| CN-105452233-A | Piperidine and azepane derivatives as prokineticin receptor modulators | TAKEDA PHARMACEUTICALS CO | 2016-03-30 | — | — | CN | disclosed |
| CN-103827133-B | Estra-1, 3,5(10), 16-tetraene-3-carboxamide derivatives, method for the production thereof, pharmaceutical preparations containing the same, and use thereof for producing medicaments | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2015-11-25 | — | — | CN | disclosed |
| CN-105008382-A | Estra-1, 3,5(10), 16-tetraene-3-carboxamides for the inhibition of 17 beta-hydroxysteroid dehydrogenase (AKR 1C 3) | Bayer Pharma AG | 2015-10-28 | — | — | CN | disclosed |
| CN-103080080-B | 6,7-dihydro-5H-benzo [7] takes turns ene derivative, its preparation method, the pharmaceutical preparation comprising it and its purposes for the preparation of medicine | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2015-08-26 | — | — | CN | disclosed |
| CN-104781259-A | BET protein inhibiting 5-aryltriazoloazepines | Bayer Pharma AG | 2015-07-15 | — | — | CN | disclosed |
| CN-103596941-B | Anti-viral compounds | ABBVIE INC | 2015-07-08 | — | — | CN | disclosed |
| CN-1527821-A | Process for preparing aminopyrimidine compounds | — | 2004-09-08 | — | — | CN | disclosed |
| CN-1419558-A | Process for preparing camptothecin | YAKULT HONSHA KK (JP) | 2003-05-21 | — | — | CN | disclosed |
| CN-1106371-C | Liquid crystal compounds having perfluoroether terminal moieties | MINNESOTA MINING & MFG (US) | 2003-04-23 | — | — | CN | disclosed |
| CN-1292005-A | Substantially fluorinated ionomers | DU PONT (US) | 2001-04-18 | — | — | CN | disclosed |
| CN-1166823-A | Liquid crystal compounds having perfluoroether terminal portions | MINNESOTA MINING & MFG (US) | 1997-12-03 | — | — | CN | disclosed |
| CN-1066271-A | 14 β-H-14-and 15-ethylene linkage-11 beta-aryl-4-estrene | SCHERING AG (DE) | 1992-11-18 | — | — | CN | disclosed |