Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AURKA | O14965 | 1/20 | 0.33 |
| ▸ | KDR | P35968 | 1/20 | 0.33 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2466575 | 0.96 | AURKA (0.32) | AURKAKDRKDM4CHDAC1HDAC6 | |
| SCHEMBL2460308 | 0.83 | KDM4C (0.38) | KDM4C | |
| SCHEMBL7196515 | 0.77 | HDAC1 (0.32) | AURKAKDRHDAC1HDAC6 | |
| Hydrochloric Acid SCHEMBL27951974 | 0.71 | — | — | |
| SCHEMBL27469700 | 0.70 | KDM4C (0.31) | KDM4C | |
| SCHEMBL8548677 | 0.70 | AURKA (0.35) | AURKAKDRKDM4CHDAC1HDAC6 | |
| Hydrochloric Acid SCHEMBL17529926 | 0.66 | — | — | |
| Hydrochloric Acid SCHEMBL5827691 | 0.66 | — | — | |
| Hydrochloric Acid SCHEMBL781796 | 0.66 | — | — | |
| Hydrochloric Acid SCHEMBL27548456 | 0.66 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1097059-C | Method for preparing thermoplastic elastomer | BAYER AG (DE) | 2002-12-25 | — | — | CN | disclosed |
| CN-1228790-A | Method for producing thermoplastic elastomers | BAYER AG (DE) | 1999-09-15 | — | — | CN | disclosed |