Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | MMP1 | P03956 | 1/20 | 0.36 |
| ▸ | MMP8 | P22894 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23813893 | 0.84 | CYP2D6 (0.39) | CYP2D6CYP2C19MMP1MMP8MAPT | |
| SCHEMBL23813828 | 0.84 | CYP2D6 (0.39) | CYP2D6CYP2C19MMP1MMP8MAPT | |
| SCHEMBL27445798 | 0.82 | — | — | |
| SCHEMBL23071956 | 0.81 | — | — | |
| SCHEMBL27447470 | 0.80 | CYP2D6 (0.36) | CYP2D6CYP2C19MMP1MMP8MAPT | |
| SCHEMBL19201193 | 0.79 | FFAR2 (0.32) | MMP1 | |
| SCHEMBL19201191 | 0.79 | FFAR2 (0.32) | MMP1 | |
| SCHEMBL12895022 | 0.78 | CYP2D6 (0.52) | CYP2D6CYP2C19MMP1MMP8MAPT | |
| SCHEMBL23813895 | 0.78 | — | — | |
| SCHEMBL27376558 | 0.77 | ELANE (0.33) | MMP1MMP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12029736-B2 | Camptothecin derivatives and conjugates thereof | MEDIBOSTON LIMITED (HK) | 2024-07-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12029736-B2 | Camptothecin derivatives and conjugates thereof | TOP2A, TOP1, XPA | CYP2D6 1898/4885CYP2C19 1974/4885MMP1 3910/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.