Acrylic Acid

Acrylic Acid

SCHEMBL27448708

C=C.C=CC(=O)O.C=CC(=O)OCC=CC

nearest known ligand 0.42

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Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
TSHR P16473 8/20 0.42
HPGD P15428 1/20 0.41
ALDH1A1 P00352 4/20 0.41
TP53 P04637 3/20 0.41
HIF1A Q16665 3/20 0.41
CYP3A4 P08684 2/20 0.41
HSD17B10 Q99714 2/20 0.41
LMNA P02545 1/20 0.39
MAPK1 P28482 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.37
THRB P10828 2/20 0.35
ALOX15 P16050 1/20 0.31
HCAR2 Q8TDS4 1/20 0.31
MAPT P10636 1/20 0.30
CACNA1B Q00975 1/20 0.30
APBA1 Q02410 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Acrylic Acid SCHEMBL28039947 0.98 TSHR (0.44) TSHRHPGDALDH1A1TP53HIF1A
Acrylic Acid SCHEMBL28806769 0.94 TSHR (0.41) TSHRHPGDALDH1A1TP53HIF1A
Ethylene SCHEMBL27355303 0.94 TSHR (0.47) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL491231 0.92
SCHEMBL27947504 0.92 TSHR (0.48) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL237830 0.92
Benzene SCHEMBL28128787 0.90 TSHR (0.44) TSHRHPGDALDH1A1TP53HIF1A
Formaldehyde SCHEMBL27599679 0.90 TSHR (0.47) TSHRHPGDALDH1A1TP53HIF1A
Propene SCHEMBL28181465 0.90 TSHR (0.47) TSHRHPGDALDH1A1TP53HIF1A
Methane SCHEMBL27884431 0.90 TSHR (0.47) TSHRHPGDALDH1A1TP53HIF1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1134509-C Thermoplastic composition based on polyamide ͨ�õ�����˾ 2004-01-14 CN claimed
CN-1276395-A Thermoplastic composition based on polyamide ATOCHEM ELF SA (FR) 2000-12-13 CN claimed
CN-1134509-C Thermoplastic composition based on polyamide ͨ�õ�����˾ 2004-01-14 CN disclosed
CN-1276395-A Thermoplastic composition based on polyamide ATOCHEM ELF SA (FR) 2000-12-13 CN disclosed