Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 4/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | CASP1 | P29466 | 1/20 | 0.34 |
| ▸ | BLM | P54132 | 1/20 | 0.34 |
| ▸ | CASP7 | P55210 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.34 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27548491 | 0.85 | PPARG (0.48) | PPARGMAPTALDH1A1HDAC3HDAC4 | |
| SCHEMBL27450178 | 0.84 | PPARG (0.53) | PPARGMAPTPOLBALDH1A1HPGD | |
| SCHEMBL6307965 | 0.83 | PPARG (0.47) | PPARGMAPTPOLBALDH1A1MEN1 | |
| SCHEMBL27465431 | 0.83 | PPARG (0.52) | PPARGHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL6389924 | 0.81 | PPARG (0.46) | PPARGMAPTPOLBALDH1A1KDM4E | |
| SCHEMBL6134452 | 0.81 | PPARG (0.75) | PPARGMAPTPOLBALDH1A1KDM4E | |
| SCHEMBL6134751 | 0.80 | PPARG (0.71) | PPARGMAPTPOLBALDH1A1KDM4E | |
| SCHEMBL6307886 | 0.79 | PPARG (0.58) | PPARGMAPTPOLBALDH1A1KDM4E | |
| SCHEMBL27449644 | 0.79 | PPARG (0.76) | PPARGHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL27449649 | 0.78 | PPARG (0.48) | PPARGMC4R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1135224-C | Benzimidazole derivatives | ����ҩƷ��ҵ��ʽ���� | 2004-01-21 | — | — | CN | disclosed |
| CN-1268123-A | Benzimidazole derivatives | FUJISAWA PHARMACEUTICAL CO (JP) | 2000-09-27 | — | — | CN | disclosed |