Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 4/20 | 0.36 |
| ▸ | TP53 | P04637 | 2/20 | 0.36 |
| ▸ | CSF1R | P07333 | 1/20 | 0.34 |
| ▸ | KIT | P10721 | 1/20 | 0.34 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.34 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.34 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.34 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.34 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.34 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.34 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.34 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | MC4R | P32245 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27448718 | 0.85 | PPARG (0.48) | PPARGMAPTTP53HDAC3HDAC4 | |
| SCHEMBL27450178 | 0.84 | PPARG (0.53) | PPARGMAPTHDAC3HDAC4HDAC1 | |
| SCHEMBL6308006 | 0.83 | PPARG (0.47) | PPARGMAPTTP53CSF1RKIT | |
| SCHEMBL27465431 | 0.83 | PPARG (0.52) | PPARGHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL6303364 | 0.81 | PPARG (0.46) | PPARGMAPTTP53ALDH1A1SMN1; SMN2 | |
| SCHEMBL6134256 | 0.81 | PPARG (0.75) | PPARGMAPTTP53CSF1RKIT | |
| SCHEMBL6301259 | 0.80 | PPARG (0.71) | PPARGMAPTTP53CSF1RKIT | |
| SCHEMBL27449644 | 0.79 | PPARG (0.76) | PPARGHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL27449649 | 0.78 | PPARG (0.48) | PPARGMC4R | |
| SCHEMBL6308742 | 0.76 | PPARG (0.56) | PPARGMAPTTP53CSF1RKIT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1135224-C | Benzimidazole derivatives | ����ҩƷ��ҵ��ʽ���� | 2004-01-21 | — | — | CN | disclosed |
| CN-1268123-A | Benzimidazole derivatives | FUJISAWA PHARMACEUTICAL CO (JP) | 2000-09-27 | — | — | CN | disclosed |