Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 14/20 | 0.57 |
| ▸ | RPS6KB1 | P23443 | 5/20 | 0.43 |
| ▸ | AURKA | O14965 | 3/20 | 0.43 |
| ▸ | AURKB | Q96GD4 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7572756 | 0.88 | ALDH1A1 (0.45) | PARP1 | |
| Methane SCHEMBL8598912 | 0.86 | ALDH1A1 (0.44) | PARP1 | |
| SCHEMBL7564071 | 0.83 | CFTR (0.49) | PARP1 | |
| SCHEMBL27449612 | 0.82 | PARP1 (0.51) | PARP1RPS6KB1AURKAAURKB | |
| SCHEMBL30661004 | 0.79 | IKBKB (0.60) | PARP1 | |
| SCHEMBL461849 | 0.79 | IKBKB (0.60) | PARP1 | |
| SCHEMBL27449144 | 0.79 | PARP1 (0.51) | PARP1 | |
| SCHEMBL27418513 | 0.79 | PARP1 (0.51) | PARP1RPS6KB1AURKA | |
| Hydrochloric Acid SCHEMBL31161184 | 0.78 | IKBKB (0.58) | PARP1 | |
| SCHEMBL28276351 | 0.78 | IKBKB (0.58) | PARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1116285-C | Bis(acridinecarboxamide) and Bis(phenazinecarboxamide) as antitumour agents | XENOVA LTD (GB) | 2003-07-30 | — | — | CN | claimed |
| CN-1116285-C | Bis(acridinecarboxamide) and Bis(phenazinecarboxamide) as antitumour agents | XENOVA LTD (GB) | 2003-07-30 | — | — | CN | disclosed |
| CN-1240430-A | Bis(acridinecarboxamide) and Bis(phenazinecarboxamide) as antitumour agents | XENOVA LTD (GB) | 2000-01-05 | — | — | CN | disclosed |