Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 8/20 | 0.53 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.37 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.37 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.37 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.37 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.37 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.37 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.37 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.37 |
| ▸ | VDR | P11473 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27450620 | 0.88 | PPARG (0.55) | PPARGLMNAHDAC3HDAC4HDAC1 | |
| SCHEMBL27465432 | 0.88 | PPARG (0.53) | PPARGLMNAHDAC3HDAC4HDAC1 | |
| SCHEMBL27450180 | 0.88 | PPARG (0.53) | PPARGLMNAHDAC3HDAC4HDAC1 | |
| SCHEMBL27524156 | 0.81 | PPARG (0.47) | PPARGSMN1; SMN2ALDH1A1MC4RALOX5AP | |
| SCHEMBL7649138 | 0.79 | PPARG (0.77) | PPARGLMNAHDAC3HDAC4HDAC1 | |
| SCHEMBL27450178 | 0.79 | PPARG (0.53) | PPARGHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL27467908 | 0.78 | PPARG (0.54) | PPARGLMNAHDAC3HDAC4HDAC1 | |
| SCHEMBL6170044 | 0.77 | PPARG (0.64) | PPARGLMNAHDAC3HDAC4HDAC1 | |
| SCHEMBL27465431 | 0.77 | PPARG (0.52) | PPARGHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL6169108 | 0.77 | PPARG (0.63) | PPARGLMNAHDAC3HDAC4HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1135224-C | Benzimidazole derivatives | ����ҩƷ��ҵ��ʽ���� | 2004-01-21 | — | — | CN | disclosed |
| CN-1268123-A | Benzimidazole derivatives | FUJISAWA PHARMACEUTICAL CO (JP) | 2000-09-27 | — | — | CN | disclosed |