Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 2/20 | 0.47 |
| ▸ | ALOX5AP | P20292 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | MC4R | P32245 | 9/20 | 0.41 |
| ▸ | MC5R | P33032 | 1/20 | 0.41 |
| ▸ | MC3R | P41968 | 1/20 | 0.41 |
| ▸ | MC1R | Q01726 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | TNF | P01375 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27491510 | 0.86 | PPARG (0.45) | PPARGALOX5APALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL27449185 | 0.81 | PPARG (0.53) | PPARGALOX5APALDH1A1SMN1; SMN2MC4R | |
| SCHEMBL27465432 | 0.81 | PPARG (0.53) | PPARGALOX5APSMN1; SMN2MC4RMC5R | |
| SCHEMBL27450180 | 0.81 | PPARG (0.53) | PPARGALOX5APSMN1; SMN2MC4RMC5R | |
| SCHEMBL27449649 | 0.79 | PPARG (0.48) | PPARGMC4RMC5RMC3RMC1R | |
| SCHEMBL6169166 | 0.79 | PPARG (0.57) | PPARGALOX5APALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL1178714 | 0.78 | PPARG (0.64) | PPARGALOX5APALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL27506551 | 0.78 | PPARG (0.45) | PPARGALOX5APALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL27450620 | 0.77 | PPARG (0.55) | PPARGALOX5APALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL27508179 | 0.76 | PPARG (0.55) | PPARGALDH1A1MAPTSMN1; SMN2TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1211238-A | Benzimidazole derivatives | FUJISAWA PHARMACEUTICAL CO (JP) | 1999-03-17 | — | — | CN | disclosed |