Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.50 |
| ▸ | CYP19A1 | P11511 | 4/20 | 0.50 |
| ▸ | OXER1 | Q8TDS5 | 4/20 | 0.50 |
| ▸ | MAPT | P10636 | 4/20 | 0.50 |
| ▸ | PPARG | P37231 | 3/20 | 0.50 |
| ▸ | RXRA | P19793 | 2/20 | 0.50 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.50 |
| ▸ | PTGS1 | P23219 | 4/20 | 0.47 |
| ▸ | F7 | P08709 | 3/20 | 0.47 |
| ▸ | F3 | P13726 | 3/20 | 0.47 |
| ▸ | PPARA | Q07869 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | PPARD | Q03181 | 2/20 | 0.47 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.47 |
| ▸ | NR1I2 | O75469 | 2/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2744954 | 1.00 | ALDH1A1 (0.50) | ALDH1A1CYP19A1OXER1MAPTPPARG | |
| SCHEMBL12099214 | 1.00 | ALDH1A1 (0.50) | ALDH1A1CYP19A1OXER1MAPTPPARG | |
| SCHEMBL28534436 | 0.98 | ALDH1A1 (0.47) | ALDH1A1CYP19A1OXER1MAPTPPARG | |
| SCHEMBL9486198 | 0.89 | AKR1C3 (0.39) | ALDH1A1CYP19A1OXER1MAPTPPARG | |
| SCHEMBL9486204 | 0.89 | AKR1C3 (0.39) | ALDH1A1CYP19A1OXER1MAPTPPARG | |
| SCHEMBL2744936 | 0.83 | ALDH1A1 (0.58) | ALDH1A1CYP19A1OXER1MAPTPPARG | |
| SCHEMBL2744634 | 0.83 | ALDH1A1 (0.58) | ALDH1A1CYP19A1OXER1MAPTPPARG | |
| SCHEMBL2744637 | 0.83 | ALDH1A1 (0.58) | ALDH1A1CYP19A1OXER1MAPTPPARG | |
| SCHEMBL2744195 | 0.81 | ALDH1A1 (0.62) | ALDH1A1CYP19A1OXER1MAPTPPARG | |
| SCHEMBL2744198 | 0.81 | ALDH1A1 (0.62) | ALDH1A1CYP19A1OXER1MAPTPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8178708-B2 | Lipid derivatives | PRONOVA BIOPHARMA NORGE AS (NO) | 2012-05-15 | — | — | US | claimed |
| US-20120232143-A1 | LIPID DERIVATIVES | PRONOVA BIOPHARMA NORGE AS | 2012-09-13 | — | — | US | disclosed |
| US-8178708-B2 | Lipid derivatives | PRONOVA BIOPHARMA NORGE AS (NO) | 2012-05-15 | — | — | US | disclosed |
| US-20090105499-A1 | LIPID DERIVATIVES | PRONOVA BIOPHARMA NORGE AS (NO) | 2009-04-23 | — | — | US | disclosed |
| US-4264517-A | Alkylphenyl 5Z,8Z,11Z,14Z,17Z-eicosapentaenoates | G.D. SEARLE & CO. (US) | 1981-04-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120232143-A1 | LIPID DERIVATIVES | CYP4F3, STARD3, PLIN3 | ALDH1A1 1254/4885CYP19A1 588/4885OXER1 162/4885 |
| US-20090105499-A1 | LIPID DERIVATIVES | PLIN3, STARD3, CYP4F3 | ALDH1A1 1511/4885CYP19A1 727/4885OXER1 164/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.