Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | KDM1A | O60341 | 6/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | CPN1 | P15169 | 1/20 | 0.35 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.35 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.34 |
| ▸ | PADI4 | Q9UM07 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 3/20 | 0.33 |
| ▸ | CA1 | P00915 | 3/20 | 0.33 |
| ▸ | CA2 | P00918 | 3/20 | 0.33 |
| ▸ | CA9 | Q16790 | 3/20 | 0.33 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11724877 | 1.00 | ALDH1A1 (0.37) | ALDH1A1MAPK1LMNAHPGDKDM1A | |
| SCHEMBL29389040 | 1.00 | ALDH1A1 (0.37) | ALDH1A1MAPK1LMNAHPGDKDM1A | |
| SCHEMBL360381 | 0.86 | — | — | |
| SCHEMBL8118840 | 0.86 | — | — | |
| SCHEMBL2400739 | 0.86 | — | — | |
| SCHEMBL477321 | 0.83 | HPGD (0.35) | ALDH1A1MAPK1LMNAHPGDKDM1A | |
| SCHEMBL1421166 | 0.83 | HPGD (0.35) | ALDH1A1MAPK1LMNAHPGDKDM1A | |
| SCHEMBL1248249 | 0.83 | HPGD (0.35) | ALDH1A1MAPK1LMNAHPGDKDM1A | |
| SCHEMBL1159242 | 0.81 | HTR2A (0.40) | ALDH1A1MAPK1LMNAKDM1APADI4 | |
| SCHEMBL1159240 | 0.81 | HTR2A (0.40) | ALDH1A1MAPK1LMNAKDM1APADI4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024112830-A1 | INHIBITORS OF SOLUTE CARRIER FAMILY 6A MEMBER 19 (SLC6A19) AND METHODS OF USE THEREOF | MAZE THERAPEUTICS, INC. (US) | 2024-05-30 | — | — | WO | disclosed |
| CN-114105887-B | Aminopyrimidine derivative and preparation method and application thereof | 沈阳药科大学 | 2023-12-01 | — | — | CN | disclosed |
| WO-2023040537-A1 | AMINOPYRIMIDINE DERIVATIVE, PREPARATION METHOD THEREFOR AND USE THEREOF | 沈阳药科大学 | 2023-03-23 | — | — | WO | disclosed |
| CN-114105887-A | Aminopyrimidine derivative and preparation method and application thereof | 沈阳药科大学 | 2022-03-01 | — | — | CN | disclosed |